Evidence map›Paper›PMID 30595900›Full record

ArticleCurrent health sciences journal

EGFR Immunoexpression in Laryngeal Squamous Cell Carcinoma.

Liliana Cercelaru, A E Stepan, C Mărgăritescu, A Osman, Ionelia-Carmen Popa, Cristiana Eugenia Simionescu, Otilia Mărgăritescu

Abstract read
In one paragraph

Article in Current health sciences journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. To Study the Role of PTEN, EGFR and HER2 in Early Glottic Squamous Cell Carcinoma.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2023
    Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Liliana CercelaruDepartment of Pathology, University of Medicine and Pharmacy of Craiova, Romania.
A E StepanDepartment of Pathology, University of Medicine and Pharmacy of Craiova, Romania.
C MărgăritescuDepartment of Pathology, University of Medicine and Pharmacy of Craiova, Romania.
A OsmanDepartment of Anatomy, University of Medicine and Pharmacy of Craiova, Romania.
Ionelia-Carmen PopaDepartment of Pathology, University of Medicine and Pharmacy of Craiova, Romania.
Cristiana Eugenia SimionescuDepartment of Pathology, University of Medicine and Pharmacy of Craiova, Romania.
Otilia MărgăritescuDepartment of Neurosurgery, University of Medicine and Pharmacy of Craiova, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epidermal growth factor receptor (EGFR) is a tyrosine kinase molecule associated to the initial stages of neoplastic transformation. High expression of EGFR is connected to aggressive tumor behavior and high risk of metastasis and treatment failure. The aim of our study was to analyze the immunohistochemical expression of EGFR in 38 cases of laryngeal squamous cell carcinomas depending on clinicopathological parameters related to prognosis. The EGFR immunoreactions have statistical significant higher values in high grade carcinomas. Although the EGFR values were superior in advanced stages lesions, the aspect was not significant EGFR may be useful in identifying the aggressive laryngeal squamous carcinomas.

Indexed as

EGFRlaryngeal squamous cell carcinoma

Identifiers

PMID30595900
PMCPMC6286452

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.