Evidence map›Paper›PMID 30595761›Full record

ArticleDisease markers2018

Follistatin-Like 1 Is Downregulated in Morbidly and Super Obese Central-European Population.

Martin Horak, Daniela Kuruczova, Filip Zlamal, Josef Tomandl, Julie Bienertova-Vasku

Open access · hybridAbstract read
In one paragraph

Article in Disease markers, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
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  6. Review
  7. Review
  8. Article
  9. New Discovered Adipokines Associated with the Pathogenesis of Obesity and Type 2 Diabetes.Diabetes, metabolic syndrome and obesity : targets and therapy · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Martin HorakDepartment of Pathological Physiology, Faculty of Medicine, Masaryk University, Kamenice 5, Brno 625 00, Czech Republic.ORCID 0000-0003-3928-2685
Daniela KuruczovaDepartment of Pathological Physiology, Faculty of Medicine, Masaryk University, Kamenice 5, Brno 625 00, Czech Republic.
Filip ZlamalDepartment of Pathological Physiology, Faculty of Medicine, Masaryk University, Kamenice 5, Brno 625 00, Czech Republic.
Josef TomandlDepartment of Biochemistry, Faculty of Medicine, Masaryk University, Kamenice 5, Brno 625 00, Czech Republic.ORCID 0000-0001-6554-3733
Julie Bienertova-VaskuDepartment of Pathological Physiology, Faculty of Medicine, Masaryk University, Kamenice 5, Brno 625 00, Czech Republic.
Masaryk University · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Follistatin-like 1 (FSTL1) is a secreted adipomyokine with a possible link to obesity; however, its connection to extreme obesity currently remains unknown. In order to analyze such association for the very first time, we employed a unique cohort of morbidly and super obese individuals with a mean BMI of 44.77 kg/m

Indexed as

Polymorphism, Single Nucleotide3' Untranslated RegionsAdipogenesisAdolescentAdultAgedBinding SitesBiomarkersCzech RepublicDown-RegulationFemaleFollistatin-Related ProteinsHumansMaleMicroRNAsMiddle Aged3' Untranslated RegionsBiomarkersFollistatin-Related ProteinsFSTL1 protein, humanMicroRNAs

Identifiers

PMID30595761
PMCPMC6282119
OpenAlexW2901216881

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.