Evidence map›Paper›PMID 30595692›Full record

ArticleInternational journal of endocrinology2018

C1q/TNF-Related Protein5 (CTRP5) as a Biomarker to Predict Metabolic Syndrome and Each of Its Components.

Feiyu Jiang, Min Yang, Xili Zhao, Rui Liu, Gangyi Yang, Dongfang Liu, Hua Liu, Hongting Zheng, Zhiming Zhu, Ling Li

Abstract read
In one paragraph

Article in International journal of endocrinology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Feiyu JiangKey Laboratory of Diagnostic Medicine (Ministry of Education) and Department of Clinical Biochemistry, College of Laboratory Medicine, Chongqing Medical University, 400016, China.ORCID 0000-0002-3583-1096
Min YangKey Laboratory of Diagnostic Medicine (Ministry of Education) and Department of Clinical Biochemistry, College of Laboratory Medicine, Chongqing Medical University, 400016, China.
Xili ZhaoDepartment of Endocrinology, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, China.
Rui LiuDepartment of Endocrinology, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, China.
Gangyi YangDepartment of Endocrinology, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, China.ORCID 0000-0002-6458-6747
Dongfang LiuDepartment of Endocrinology, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, China.
Hua LiuDepartment of Pediatrics, University of Mississippi Medical Center, 2500 North State Street, Jackson, Mississippi, USA.
Hongting ZhengDepartment of Endocrinology, Xinqiao Hospital, Third Military Medical University, Chongqing, China.ORCID 0000-0002-6930-0103
Zhiming ZhuDepartment of Hypertension and Endocrinology, Daping Hospital, Third Military Medical University, Chongqing Institute of Hypertension, Chongqing, China.
Ling LiKey Laboratory of Diagnostic Medicine (Ministry of Education) and Department of Clinical Biochemistry, College of Laboratory Medicine, Chongqing Medical University, 400016, China.ORCID 0000-0002-0087-3034

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveC1q/TNF-related protein5 (CTRP5) is a member of the C1q/tumor necrosis factor

methodsWe performed a cross-sectional study in a Chinese population including 89 controls and 88 MetS individuals. Serum CTRP5 concentrations were determined by ELISA. The relationship between circulating CTRP5 and MetS and insulin resistance (IR) was assessed by Spearman's correlation and multiple stepwise regression analysis.

resultsCirculating CTRP5 concentrations were markedly decreased in MetS individuals relative to normal adults. Overweight/obese individuals (BMI ≥ 25 kg/m

conclusionsCirculating CTRP5 is relative to the elevated risk of MetS in humans and may be in part through the effect of insulin resistance. This trial is registered with ChiCTR-OCS-13003185.

Identifiers

PMID30595692
PMCPMC6282127

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.