Evidence map›Paper›PMID 30595311›Full record

ArticleIndian heart journal2018

Frequency and association of disabled homolog 2-interacting protein (DAB2IP) variant rs7025486 G>A with coronary artery disease risk in Indian population.

Aparna A Bhanushali, Gayatri Pradhan, A Contractor, Bibhu R Das

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Indian heart journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Aparna A BhanushaliResearch and Development, SRL Ltd Prime Square Building, Plot No 1, S. V. Road, Goregaon (W), Mumbai, 400 062, India. Electronic address: aparna.bhanushali@srl.in.
Gayatri PradhanResearch and Development, SRL Ltd Prime Square Building, Plot No 1, S. V. Road, Goregaon (W), Mumbai, 400 062, India. Electronic address: gayatri.pradhan@srl.in.
A ContractorSir H. N Reliance Foundation Hospital & Research Centre Raja Rammohan Roy Road, Prarthana Samaj, Khetwadi, Girgaon, Maharashtra, Mumbai, 400004, India. Electronic address: ascontractor@gmail.com.
Bibhu R DasResearch and Development, SRL Ltd Prime Square Building, Plot No 1, S. V. Road, Goregaon (W), Mumbai, 400 062, India. Electronic address: brdas@srl.in.
Sir H.N. Reliance Foundation Hospital and Research Centre · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genome wide association study has identified rs7025486 G>A polymorphism within DAB2IP (Disabled homolog 2-interacting protein) gene with increased risk of coronary heart disease (CAD). In this study we have determined the frequency and association of rs7025486 with CAD in Indians. The study was performed on 214 patients with CAD and 125 controls. The 'AA' genotype was associated with an increased risk in the CAD age group <50 yrs as compared to CAD age group>50 yrs (OR 3.149; P 0.034) and controls >50 yrs (OR 3.430; P 0.080). The risk allele (A) was significantly associated with premature CAD.

Indexed as

Genetic Predisposition to DiseasePolymorphism, Single NucleotideAllelesCoronary Artery DiseaseDNAFemaleGenome-Wide Association StudyGenotypeHumansIncidenceIndiaMaleMiddle Agedras GTPase-Activating ProteinsRisk FactorsDAB2IP protein, humanDNAras GTPase-Activating ProteinsAssociation studyCoronary artery diseaseGenotypingIndiansSingle nucleotide polymorphism

Identifiers

PMID30595311
PMCPMC6309282
OpenAlexW2808945690

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.