Evidence map›Paper›PMID 30595253›Full record

ArticleIndian heart journal2018

Fragmented QRS on surface electrocardiogram as a predictor of perfusion defect in patients with suspected coronary artery disease undergoing myocardial perfusion imaging.

Sepideh Hekmat, Leili Pourafkari, Mojan Ahmadi, Mohammad Reza Chavoshi, Bijan Zamani, Nader D Nader

Abstract read
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Article in Indian heart journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

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4citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Sepideh HekmatDept. of Nuclear Medicine, Iran University of Medical Sciences, Tehran, Iran. Electronic address: sepidhekmat@hotmail.com.
Leili PourafkariCardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, Iran; Dept. of Anesthesiology, University at Buffalo, Buffalo, NY, USA. Electronic address: Leili.p@gmail.com.
Mojan AhmadiCardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. Electronic address: mojan.ahmadi88@gmail.com.
Mohammad Reza ChavoshiCardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. Electronic address: chavoushi.smr@gmail.com.
Bijan ZamaniDept. of Cardiology, Ardabil University of Medical Sciences, Ardabil, Iran. Electronic address: bijanzamani@gmail.com.
Nader D NaderDept. of Anesthesiology, University at Buffalo, Buffalo, NY, USA. Electronic address: nnader@buffalo.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFragmented QRS (FQRS) on surface electrocardiogram (ECG) is associated with the presence of myocardial scar tissue and may have prognostic value after certain ischemic events. We aimed to examine the anatomical correlation of FQRS with the presence of perfusion abnormalities in patients with suspected coronary artery disease (CAD).

methodsPatients without a known history of CAD, who were referred for myocardial perfusion imaging (MPI) between January 2016 and May 2016, were enrolled. The presence of FQRS on surface ECG was evaluated. The presence of FQRS, number of leads with FQRS, and the location of FQRS as well as patient characteristics were compared in patients with normal versus abnormal MPI. Multivariate model was constructed to identify independent factors associated with perfusion defect.

resultsOne hundred four women and 94 men were enrolled. Fragmentation of anterior, lateral, and inferior leads was detected in 13 (6.5%), 17 (8.5%), and 36 (18.1%) subjects, respectively. MPI was normal in 134 (67.6%) patients. FQRS was significantly more common in patients with abnormal MPI (p < 0.001). Age (odds ratio [OR]: 1.05 [1.02-1.08]; p = 0.001), number of the leads presenting FQRS (OR: 1.46 [1.12-1.92] p = 0.006), and diabetes (OR: 2.33 [1.16-4.69]; p = 0.018) were independent predictors of the presence of perfusion defect on MPI.

conclusionIn the absence of known CAD, FQRS is associated with the presence of perfusion abnormalities. Incorporating FQRS in diagnostic armamentarium may aid us in selecting patients who may benefit from MPI.

Indexed as

Coronary Artery DiseaseCoronary CirculationCoronary VesselsCross-Sectional StudiesElectrocardiographyFemaleFollow-Up StudiesHumansMaleMiddle AgedMyocardial Perfusion ImagingPredictive Value of TestsPrognosisProspective StudiesRisk FactorsCoronary artery diseaseElectrocardiogramFragmented QRSMyocardial perfusion imaging

Identifiers

PMID30595253
PMCPMC6310744

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