Evidence map›Paper›PMID 30595117›Full record

ArticleHypertension (Dallas, Tex. : 1979)2019

MiR-192-5p in the Kidney Protects Against the Development of Hypertension.

Maria Angeles Baker, Feng Wang, Yong Liu, Alison J Kriegel, Aron M Geurts, Kristie Usa, Hong Xue, Dandan Wang, Yiwei Kong, Mingyu Liang

Open access · bronzeAbstract read
In one paragraph

Article in Hypertension (Dallas, Tex. : 1979), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 59 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Transcriptional Repression of CCL2 by KInternational journal of molecular sciences · 2025
    Article
  5. Article
  6. Article
  7. microRNA and Hypertension.Hypertension (Dallas, Tex. : 1979) · 2025
    Review
  8. Article
  9. Article
  10. TNF inhibits AQP2 expression via a miR137-dependent pathway.American journal of physiology. Renal physiology · 2024
    Article
  11. MicroRNA-195a-5p Regulates Blood Pressure by Inhibiting NKCC2A.Hypertension (Dallas, Tex. : 1979) · 2023
    Article
  12. Article
  13. Broad-acting therapeutic effects of miR-29b-chitosan on hypertension and diabetic complications.Molecular therapy : the journal of the American Society of Gene Therapy · 2022
    Article
  14. Review
  15. Article
  16. MicroRNAs in cardiovascular diseases.Medical review (2021) · 2022
    Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Maria Angeles BakerFrom the Department of Physiology, Center of Systems Molecular Medicine, Medical College of Wisconsin, Milwaukee (M.A.B., F.W., Y.L., A.J.K., A.M.G., K.U., H.X., D.W., Y.K., M.L.).
Feng WangFrom the Department of Physiology, Center of Systems Molecular Medicine, Medical College of Wisconsin, Milwaukee (M.A.B., F.W., Y.L., A.J.K., A.M.G., K.U., H.X., D.W., Y.K., M.L.).
Yong LiuFrom the Department of Physiology, Center of Systems Molecular Medicine, Medical College of Wisconsin, Milwaukee (M.A.B., F.W., Y.L., A.J.K., A.M.G., K.U., H.X., D.W., Y.K., M.L.).
Alison J KriegelFrom the Department of Physiology, Center of Systems Molecular Medicine, Medical College of Wisconsin, Milwaukee (M.A.B., F.W., Y.L., A.J.K., A.M.G., K.U., H.X., D.W., Y.K., M.L.).
Aron M GeurtsFrom the Department of Physiology, Center of Systems Molecular Medicine, Medical College of Wisconsin, Milwaukee (M.A.B., F.W., Y.L., A.J.K., A.M.G., K.U., H.X., D.W., Y.K., M.L.).
Kristie UsaFrom the Department of Physiology, Center of Systems Molecular Medicine, Medical College of Wisconsin, Milwaukee (M.A.B., F.W., Y.L., A.J.K., A.M.G., K.U., H.X., D.W., Y.K., M.L.).
Hong XueFrom the Department of Physiology, Center of Systems Molecular Medicine, Medical College of Wisconsin, Milwaukee (M.A.B., F.W., Y.L., A.J.K., A.M.G., K.U., H.X., D.W., Y.K., M.L.).
Dandan WangFrom the Department of Physiology, Center of Systems Molecular Medicine, Medical College of Wisconsin, Milwaukee (M.A.B., F.W., Y.L., A.J.K., A.M.G., K.U., H.X., D.W., Y.K., M.L.).
Yiwei KongFrom the Department of Physiology, Center of Systems Molecular Medicine, Medical College of Wisconsin, Milwaukee (M.A.B., F.W., Y.L., A.J.K., A.M.G., K.U., H.X., D.W., Y.K., M.L.).
Mingyu LiangFrom the Department of Physiology, Center of Systems Molecular Medicine, Medical College of Wisconsin, Milwaukee (M.A.B., F.W., Y.L., A.J.K., A.M.G., K.U., H.X., D.W., Y.K., M.L.).
Medical College of Wisconsin · US

Funding

Stem Cell CoreP01GM066730 · NIGMS · MEDICAL COLLEGE OF WISCONSIN · PI DASH, RANJAN K · 2003 to 2019
$23.6M
Research ServicesP01HL082798 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI GREENE, ANDREW S. · 2006 to 2015
$22.0M
Regulatory RNA in Hypertension and Renal InjuryR01HL121233 · NHLBI · UNIVERSITY OF ARIZONA · PI MINGYU LIANG · 2014 to 2026
$3.8M
MicroRNA-29b and Endothelial FunctionR01HL125409 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI LIANG, MINGYU, WIDLANSKY, MICHAEL E · 2015 to 2018
$2.0M
NHLBI NIH HHS P01 HL082798NHLBI NIH HHS R01 HL121233NHLBI NIH HHS R01 HL125409NIGMS NIH HHS P01 GM066730
6 · The paper itself

Abstract

MicroRNA miR-192-5p is one of the most abundant microRNAs in the kidney and targets the mRNA for ATP1B1 (β1 subunit of Na

Indexed as

Angiotensin IIAnimalsBlood PressureHumansHypertensionKidneyMaleMicroRNAsRatsRats, Inbred DahlSodium-Potassium-Exchanging ATPaseAngiotensin IIATP1B1 protein, humanMicroRNAsMIRN192 microRNA, humanMIRN192 microRNA, ratSodium-Potassium-Exchanging ATPasediethypertensionkidneymicroRNArats

Identifiers

PMID30595117
PMCPMC6339564
OpenAlexW2907233970

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.