ArticleJournal of materials science. Materials in medicine2018
Keratin nanoparticles-coating electrospun PVA nanofibers for potential neural tissue applications.
Article in Journal of materials science. Materials in medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 46 citations in OpenAlex.
- Exploration of biomaterial and stem cell-based strategies for promoting neuronal regeneration and creating engineered 3D in-vitro disease models.Journal of translational medicine · 2025Review
- Micro- and Nanostructured Fibrous Composites via Electro-Fluid Dynamics: Design and Applications for Brain.Pharmaceutics · 2024Review
- Fucoidan and microtopography on polyvinyl alcohol hydrogels guided axons and enhanced neuritogenesis of pheochromocytoma 12 (PC12) cells.Biomedical materials (Bristol, England) · 2023Article
- Hybrid Systems of Nanofibers and Polymeric Nanoparticles for Biological Application and Delivery Systems.Micromachines · 2023Review
- Electrospun non-wovens potential wound dressing material based on polyacrylonitrile/chicken feathers keratin nanofiber.Scientific reports · 2022Article
- Bioactive Keratin and Fibroin Nanoparticles: An Overview of Their Preparation Strategies.Nanomaterials (Basel, Switzerland) · 2022Review
- Fabrication of polyvinyl alcohol-graphene nanosheet nanocomposite loading of omega-3 fatty acids for ceramic engineering.Iranian journal of basic medical sciences · 2022Article
- Design of Asymmetric Nanofibers-Membranes Based on Polyvinyl Alcohol and Wool-Keratin for Wound Healing Applications.Journal of functional biomaterials · 2021Article
- Design of a biofluid-absorbing bioactive sandwich-structured Zn-Si bioceramic composite wound dressing for hair follicle regeneration and skin burn wound healing.Bioactive materials · 2021Article
- Silk fibroin nanoscaffolds for neural tissue engineering.Journal of materials science. Materials in medicine · 2020Article
- New forms of electrospun nanofiber materials for biomedical applications.Journal of materials chemistry. B · 2020Review
- Hair keratin promotes wound healing in rats with combined radiation-wound injury.Journal of materials science. Materials in medicine · 2020Article
- Stretchable collagen-coated polyurethane-urea hydrogel seeded with bladder smooth muscle cells for urethral defect repair in a rabbit model.Journal of materials science. Materials in medicine · 2019Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
Abstract
Keratin has the potential to improve biocompatibility and bioactivity of polymeric nanofibers. However, the addition of keratin into the blend nanofiber would decrease the mechanical properties of nanofibers due to the poor spinnability of keratin, and caused inhomogeneous distribution of keratin inside the nanofibers. Therefore, polymeric nanofibers surface-modified with keratin nanoparticles would improve the hydrophility and mechanical property. In this study, keratose (oxidative keratin, KOS) nanoparticles-coating PVA nanofibers (KNPs/PVA) were fabricated by electrospray deposition after electrospinning and acted on neural cells. The chemical conformation, mechanical properties and wettability of KNPs/PVA nanofibers were characterized. The KNPs/PVA nanofibers provided better wettability and stronger mechanical properties compared to KOS/PVA blend nanofibers at the same mass ratio of KOS to PVA. Furthermore, KNPs/PVA nanofibers displayed better cyto-biocompatibility in terms of cell morphology, adhesion and proliferation compared with PVA nanofibers and KOS/PVA blend nanofibers. These results suggested that polymeric nanofibers surface-modified with KOS nanoparticles can provide superior wettability, mechanical properties and biocompatibility by comparison with the blend nanofibers.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.