ArticleJournal of ophthalmic inflammation and infection2018
Urinary β2-microglobulin and disease activity in patients with tubulointerstitial nephritis and uveitis syndrome.
Article in Journal of ophthalmic inflammation and infection, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 23 citations in OpenAlex.
- Drug-induced tubulointerstitial nephritis and uveitis syndrome in a nationwide surveillance.Eye (London, England) · 2025Article
- A Comprehensive Review of Tubulointerstitial Nephritis and Uveitis (TINU) Syndrome.Biomedicines · 2025Review
- Clinical outcomes in paediatric tubulointerstitial nephritis and uveitis syndrome (TINU).Eye (London, England) · 2024Article
- Diagnosis and Characteristics of Presentation of Tubulointerstitial Nephritis and Uveitis Syndrome During the COVID-2019 Pandemic.Ocular immunology and inflammation · 2024Article
- Ocular manifestations and clinical outcomes in Tubulointerstitial Nephritis and Uveitis Syndrome (TINU).Eye (London, England) · 2024Article
- Diagnostic and Management Strategies of Tubulointerstitial Nephritis and Uveitis Syndrome (TINU): Current Perspectives.Clinical ophthalmology (Auckland, N.Z.) · 2023Review
- Renal Prognosis in Children With Tubulointerstitial Nephritis and Uveitis Syndrome.Kidney international reports · 2021Article
- Tubulointerstitial nephritis and uveitis syndrome in an adolescent female: a case report.Journal of medical case reports · 2021Article
- Classification Criteria for Tubulointerstitial Nephritis With Uveitis Syndrome.American journal of ophthalmology · 2021Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundUrinary β2-microglobulin (Uβ2M) is elevated in tubulointerstitial nephritis and uveitis (TINU) syndrome and has emerged as an important diagnostic tool. This study aims to determine whether Uβ2M correlates with uveitis activity in TINU.
methodsRetrospective observational case series of nine patients with TINU and ≥ 30 days follow-up. Presenting symptoms, visual acuity, uveitis characteristics, follow-up, Uβ2M, serum creatinine (SCr), urinalysis, and renal biopsy results were collected.
resultsA correlation between Uβ2M and anterior chamber (AC) cell (r = 0.69, 95% CI 0.46-0.84), flare (r = 0.65, 95% CI 0.39-0.81), trended toward a stronger correlation than SCr and AC cell (r = 0.59, 95% CI 0.29-0.79), flare (r = 0.52, 95% CI 0.19-0.75). Uβ2M decreased over 1-2 years while SCr returned to normal within a few months.
conclusionsUβ2M correlate with uveitis activity and trend down over the course of TINU. Uβ2M may serve as a useful tool in determining where patients are in their systemic disease course.
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