ArticleEnvironmental toxicology and pharmacology2019
Organochlorine pesticides and polychlorinated biphenyls (PCBs) in early adulthood and blood lipids over a 23-year follow-up.
Article in Environmental toxicology and pharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed, 25 citations in OpenAlex.
- Article
- Plasma concentrations of persistent organic pollutants and pancreatic cancer risk.International journal of epidemiology · 2022Article
- Garbage in garbage out: the contribution of our industrial advancement to wastewater degeneration.Environmental science and pollution research international · 2020Review
- Synthetic Chemicals and Cardiometabolic Health Across the Life Course Among Vulnerable Populations: a Review of the Literature from 2018 to 2019.Current environmental health reports · 2020Review
- Summary data of serum concentrations of 32 persistent organic pollutants in young adults in relation to summary scores of persistent organic pollutants.Data in brief · 2019Article
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Authors and funding
5 authors at 4 institutions in 3 countries.
Funding
Abstract
backgroundSome evidence in humans suggests that persistent organic pollutants (POPs), including organochlorine pesticides (OCPs) and polychlorinated biphenyls (PCBs), may alter the blood lipid composition. This study analyzed associations between serum POPs concentrations in young adulthood with blood lipid levels up to 23 years later.
methodsSerum POPs were measured in year 2 of follow-up (n = 180 men and women, ages: 20-32y), and plasma lipids in follow-up years 2, 7, 10, 15, 20 and 25. 32 POPs were detectable in ≥75% of participants (23 PCBs, 8 OCPs and PBB-153). We created summary scores for PCBs and OCPs for both wet-weight, and lipid standardized (LP) concentrations. We used repeated measures regression adjusting for demographic factors, BMI, smoking, diabetes status, among others.
resultsWe observed positive associations of the 23 LP-PCB score with total cholesterol (β
conclusionsPCBs and PBB-153 measured in young adulthood were positively associated with prospective alterations in most blood lipid components, with evidence of effect modification by BMI. Further longitudinal studies with multiple measures of POPs overtime are needed.
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