Evidence map›Paper›PMID 30594454›Full record

SynthesisParkinsonism & related disorders2019

A meta-analysis: Parkinson's disease and dual-task walking.

Tiphanie E Raffegeau, Lisa M Krehbiel, Nyeonju Kang, Frency J Thijs, Lori J P Altmann, James H Cauraugh, Chris J Hass

Registry-linked trialAbstract readMeta-AnalysisReview
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Parkinsonism & related disorders, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07411365 (Efficacy of Dual-task Telerehabilitation to Prevent Worsening in Activities of Daily Living in People With Parkinson's Disease at High Risk for Dementia), which is not on this map. Cited by 101 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
101citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07411365 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Efficacy of Dual-task Telerehabilitation to Prevent Worsening in Activities of Daily Living in People With Parkinson's Disease at High Risk for Dementia: A Proof-of-concept Study

TypeinterventionalSponsorUniversity Hospital TuebingenRan2026 to 2027Enrolled42ConditionsPARKINSON DISEASE (Disorder), Mild Cognitive Impairment (MCI)ArmsDual-task Cognitive Motor Training, Cognitive Motor Training
3 · Its place in the literature

Who cites it

101 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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  2. Combinations of physical and cognitive training for subcortical neurodegenerative diseases with physical, cognitive and behavioral symptoms: a systematic review.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024
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41 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tiphanie E RaffegeauApplied Physiology and Kinesiology Department, University of Florida, Gainesville, FL, USA.
Lisa M KrehbielApplied Physiology and Kinesiology Department, University of Florida, Gainesville, FL, USA.
Nyeonju KangApplied Physiology and Kinesiology Department, University of Florida, Gainesville, FL, USA; Division of Sport Science & Sport Science Institute, Incheon National University, Seoul, South Korea.
Frency J ThijsApplied Physiology and Kinesiology Department, University of Florida, Gainesville, FL, USA.
Lori J P AltmannDepartment of Speech, Language, and Hearing Sciences, University of Florida, Gainesville, FL, USA.
James H CauraughApplied Physiology and Kinesiology Department, University of Florida, Gainesville, FL, USA.
Chris J HassApplied Physiology and Kinesiology Department, University of Florida, Gainesville, FL, USA. Electronic address: cjhass@aa.ufl.edu.

Funding

Research Training in Non-Pharmacological Interventions for Cognition in Aging, MCI, and Alzheimer's DiseaseT32AG020499 · NIA · UNIVERSITY OF FLORIDA · PI MARSISKE, MICHAEL, SMITH, GLENN E. · 2003 to 2024
$3.7M
NIA NIH HHS T32 AG020499
6 · The paper itself

Abstract

A growing body of literature has reported the effects of dual tasks on gait performance in people with Parkinson's disease (PD). The purpose of this meta-analysis was to synthesize the existing literature and quantify the overall influence of dual tasks on gait performance in PD. A thorough literature search was conducted, and 19 studies met the stringent inclusion criteria. Two moderator variable analyses examined the dual-task effect by: (a) mean single-task gait speed for each study (≥1.1 m/s or < 1.1 m/s), and (b) the type of dual task (arithmetic, language, memory, and motor). Three main findings were revealed by a random effects model analysis. First, a strong negative effect of dual tasks on walking performance (SMD = -0.68) confirmed that gait performance is adversely affected by dual tasks in people with PD. Second, the significant negative effect of dual tasks is present regardless of the mean level of single-task gait speed in a study. Third, dual-task walking speed deteriorates regardless of the type of dual task. Together, these results confirm that dual tasks severely affect walking performances in people with PD.

Indexed as

AttentionGaitHumansParkinson DiseasePsychomotor PerformanceTask Performance and AnalysisWalkingCognitionDual-taskInterferenceParkinson'sWalk

Identifiers

PMID30594454
PMCPMC8487457

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.