Evidence map›Paper›PMID 30594268›Full record

ArticleThe American journal of tropical medicine and hygiene2019

Respiratory Viral Infection: An Underappreciated Cause of Acute Febrile Illness Admissions in Southern Sri Lanka.

L Gayani Tillekeratne, Champica K Bodinayake, Ryan Simmons, Ajith Nagahawatte, Vasantha Devasiri, Wasantha Kodikara Arachchi, Bradly P Nicholson, Lawrence P Park, Sky Vanderburg, Ruvini Kurukulasooriya and 4 more

Open access · bronzeAbstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 2 countries.

L Gayani TillekeratneDuke University, Durham, North Carolina.
Champica K BodinayakeFaculty of Medicine, University of Ruhuna, Galle, Sri Lanka.
Ryan SimmonsDuke Global Health Institute, Durham, North Carolina.
Ajith NagahawatteFaculty of Medicine, University of Ruhuna, Galle, Sri Lanka.
Vasantha DevasiriFaculty of Medicine, University of Ruhuna, Galle, Sri Lanka.
Wasantha Kodikara ArachchiTeaching Hospital Karapitiya, Galle, Sri Lanka.
Bradly P NicholsonDuke-Ruhuna Collaborative Research Centre, Galle, Sri Lanka.
Lawrence P ParkDuke Global Health Institute, Durham, North Carolina.
Sky VanderburgDuke-Ruhuna Collaborative Research Centre, Galle, Sri Lanka.
Ruvini KurukulasooriyaDuke-Ruhuna Collaborative Research Centre, Galle, Sri Lanka.
Aruna Dharshan De SilvaGeneral Sir Kotelawala Defence University, Ratmalana, Sri Lanka.
Truls ØstybeDuke-Ruhuna Collaborative Research Centre, Galle, Sri Lanka.
Megan E RellerDuke-Ruhuna Collaborative Research Centre, Galle, Sri Lanka.
Christopher W WoodsDuke-Ruhuna Collaborative Research Centre, Galle, Sri Lanka.
Duke University · USUniversity of Ruhuna · LKGeneral Sir John Kotelawala Defence University · LKTeaching Hospital Kandy · LK

Funding

Vanderbilt-Emory-Cornell-Duke Global Health Fellowship Consortium-Expanding Diversity for Global Equity (EDGE)D43TW009337 · FIC · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ALIYU, MUKTAR HASSAN, HEIMBURGER, DOUGLAS CORBETT · 2017 to 2021
$6.3M
Vanderbilt-Emory-Cornell-Duke Consortium for Global Health Fellows (VECDor)R25TW009337 · FIC · VANDERBILT UNIVERSITY MEDICAL CENTER · PI HEIMBURGER, DOUGLAS CORBETT, VERMUND, STEN H. · 2012 to 2016
$6.3M
Novel Diagnostics to Improve Antimicrobial Stewardship for Acute Respiratory Tract Infections in Resource-Limited SettingsK23AI125677 · NIAID · DUKE UNIVERSITY · PI TILLEKERATNE, GAYANI · 2017 to 2021
$905k
FIC NIH HHS D43 TW009337FIC NIH HHS R25 TW009337NIAID NIH HHS K23 AI125677
6 · The paper itself

Abstract

The contribution of respiratory viruses to acute febrile illness (AFI) burden is poorly characterized. We describe the prevalence, seasonality, and clinical features of respiratory viral infection among AFI admissions in Sri Lanka. We enrolled AFI patients ≥ 1 year of age admitted to a tertiary care hospital in southern Sri Lanka, June 2012-October 2014. We collected epidemiologic/clinical data and a nasal or nasopharyngeal sample that was tested using polymerase chain reaction (Luminex NxTAG, Austin, TX). We determined associations between weather data and respiratory viral activity using the Spearman correlation and assessed respiratory virus seasonality using a Program for Appropriate Technology definition. Bivariable and multivariable regression analyses were conducted to identify features associated with respiratory virus detection. Among 964 patients, median age was 26.2 years (interquartile range 14.6-39.9) and 646 (67.0%) were male. One-fifth (203, 21.1%) had respiratory virus detected: 13.9% influenza, 1.4% human enterovirus/rhinovirus, 1.4% parainfluenza virus, 1.1% respiratory syncytial virus, and 1.1% human metapneumovirus. Patients with respiratory virus identified were younger (median 9.8 versus 27.7 years,

Indexed as

AdolescentAdultAgedChildChild, PreschoolFemaleFeverHospitalizationHumansMaleMiddle AgedOdds RatioRespiratory Tract InfectionsRisk FactorsSeasonsSri Lanka

Identifiers

PMID30594268
PMCPMC6402941
OpenAlexW2907503882

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.