Evidence map›Paper›PMID 30594192›Full record

ArticleBMC health services research2018

Choosing wisely? Quantifying the extent of three low value psychotropic prescribing practices in Australia.

Jonathan Brett, Helga Zoega, Nicholas A Buckley, Benjamin J Daniels, Adam G Elshaug, Sallie-Anne Pearson

Open access · goldAbstract read
In one paragraph

Article in BMC health services research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Jonathan BrettMedicines Policy Research Unit, Centre for Big Data Research in Health, University of New South Wales, Sydney, NSW, 2052, Australia. J.Brett@unsw.edu.au.ORCID http://orcid.org/0000-0003-3065-7495
Helga ZoegaMedicines Policy Research Unit, Centre for Big Data Research in Health, University of New South Wales, Sydney, NSW, 2052, Australia.
Nicholas A BuckleySchool of Medicine, The University of Sydney, Sydney, NSW, Australia.
Benjamin J DanielsMedicines Policy Research Unit, Centre for Big Data Research in Health, University of New South Wales, Sydney, NSW, 2052, Australia.
Adam G ElshaugMenzies Centre for Health Policy, The University of Sydney, Sydney, Australia.
Sallie-Anne PearsonMedicines Policy Research Unit, Centre for Big Data Research in Health, University of New South Wales, Sydney, NSW, 2052, Australia.
The University of Sydney · AUUNSW Sydney · AUUniversity of Iceland · IS

Funding

National Health and Medical Research Council 1060407National Health and Medical Research Council 1094304National Health and Medical Research Council 1109626
6 · The paper itself

Abstract

backgroundThe global Choosing Wisely campaign has identified the following psychotropic prescribing as low-value (harmful or wasteful): (1) benzodiazepine use in the elderly, (2) antipsychotic use in dementia and (3) prescribing two or more antipsychotics concurrently. We aimed to quantify the extent of these prescribing practices in the Australian population.

methodsWe applied indicators to dispensing claims of a 10% random sample of Australian Pharmaceutical Benefits Scheme beneficiaries to quantify annual rates of each low-value practice from 2013 to 2016. We also assessed patient factors and direct medicine costs (extrapolated to the entire Australian population) associated with each practice in 2016.

resultsWe observed little change in the rates of the three practices between 2013 and 2016. In 2016, 15.3% of people aged ≥65 years were prescribed a benzodiazepine, 0.5% were prescribed antipsychotics in the context of dementia and 0.2% of people aged ≥18 years received two or more antipsychotics concurrently. The likelihood of elderly people receiving benzodiazepines or antipsychotics in the context of dementia increased with age and the likelihood of receiving all three practices increased with comorbidity burden. In 2016, direct medicine costs to the government of all three practices combined, extrapolated to national figures, were > $21 million AUD.

conclusionsOur indicators suggest that the frequency of these three practices has not changed appreciably in recent years and that they incur significant costs. Worryingly, people with the greatest risk of harm from these prescribing practices are often the most likely to receive them.

Indexed as

AdolescentAdultAgedAged, 80 and overAustraliaBenzodiazepinesDementiaFemaleHealth Services ResearchHumansMaleMiddle AgedPractice Guidelines as TopicPractice Patterns, Physicians'Psychotropic DrugsResidential TreatmentBenzodiazepinesPsychotropic DrugsAntipsychoticsBenzodiazepinesChoosing wiselyDementiaElderlyPolypharmacy

Identifiers

PMID30594192
PMCPMC6310957
OpenAlexW2907219783

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.