Evidence map›Paper›PMID 30594161›Full record

ArticleBMC pregnancy and childbirth2018

Acceptability of option B+ among HIV positive women receiving antenatal and postnatal care services in selected health centre's in Lusaka.

Bridget Chomba Chanda, Rosemary Ndonyo Likwa, Jessy Zgambo, Louis Tembo, Choolwe Jacobs

Abstract read
In one paragraph

Article in BMC pregnancy and childbirth, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Bridget Chomba ChandaDepartment of Paediatric and Child Health, University Teaching Hospital-HIV/AIDS Program, P.O Box, 50440, Lusaka, Zambia. chandabridget@gmail.com.
Rosemary Ndonyo LikwaDepartment of population studies and Nutrition, School of Public Health, University of Zambia, Geneva, Switzerland.
Jessy ZgamboDepartment of Epidemiology and Biostatistics, School of Public Health, University of Zambia, Lusaka, Zambia.
Louis TemboDepartment of Health Promotion and Education, School of Public Health, University of Zambia, Lilongwe, Malawi.
Choolwe JacobsDepartment of Epidemiology and Biostatistics, School of Public Health, University of Zambia, Lusaka, Zambia.

Funding

Fogarty African Bioethics Post-Doctoral Training ProgramD43TW010512 · FIC · JOHNS HOPKINS UNIVERSITY · PI Joseph Ali, NANCY E KASS · 2017 to 2026
$2.2M
FIC NIH HHS D43 TW010512
6 · The paper itself

Abstract

backgroundIn 2013, Zambia accepted the immediate operationalization of Option B+, a policy used to try and eliminate mother to child transmission. This policy requires all HIV-positive pregnant and breastfeeding women to initiate antiretroviral treatment for life regardless of CD4 count. However, not all HIV positive women accept treatment for life. This study aimed to investigate acceptability of lifelong ART (Option B+) among HIV positive women receiving antenatal and postnatal services at the university teaching hospital and Lusaka urban city clinics.

methodsThis was a cross sectional study conducted in November, 2016 to March 2017. The study population comprised of HIV positive women in their reproductive age (15-49 years). A Structured questionnaire was used to collect data in a face to face interview with the participants. Data was entered in EpiData version 3.1 and analysed using Stata version 13. Multivariate logistic regression analysis was performed to determine predictors of acceptability.

resultsOverall, 427 women participated in this study. Their mean age was 30 years. Of the 427, over half (54%) had inadequate knowledge and about 30% of the women in the study still experience stigma and discrimination.63.2% of the women had good attitude towards Option B+ and overall, the majority (77.8%) were willing to accept antiretroviral therapy for life. Multivariate analysis showed that only women with good attitude were 9.4 times more likely to accept Option B+ than those with a bad attitude [OR: 9.4: 95%CI, 5.8-15.2)].

conclusionThis study showed that in general, women accepted initiation of Option B+. However, there is still a gap in the level of knowledge of Option B+ as well as stigma and discrimination in some communities, hence there is need to intensify programs that are aimed at educating the community on the importance of ART for life, combat stigma and discrimination and consequently promote acceptability of Option B+.

Indexed as

Health Knowledge, Attitudes, PracticeAdolescentAdultAnti-HIV AgentsBreast FeedingCD4 Lymphocyte CountCross-Sectional StudiesFemaleHealth PolicyHIV SeropositivityHumansInfectious Disease Transmission, VerticalMiddle AgedPatient Acceptance of Health CarePregnancySocial DiscriminationAnti-HIV AgentsAcceptabilityAntiretroviral therapyAttitudeDiscriminationOption B +Prevention of mother to child transmission; knowledge

Identifiers

PMID30594161
PMCPMC6311017

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.