ReviewCurrent opinion in biotechnology2019
Cell-free microcompartmentalised transcription-translation for the prototyping of synthetic communication networks.
Review in Current opinion in biotechnology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
27 citing papers in PubMed.
- RNA-Based Communication in Heterogeneous Populations of Cell Mimics.ACS synthetic biology · 2026Article
- Dynamic Transcription Machineries in Protocells.Journal of the American Chemical Society · 2025Review
- ATP Regeneration from Pyruvate in the PURE System.ACS synthetic biology · 2025Article
- Cell-Free Gene Expression: Methods and Applications.Chemical reviews · 2025Review
- Tuning interfacial fluidity and colloidal stability of membranized coacervate protocells.Communications chemistry · 2024Article
- Superstructural ordering in self-sorting coacervate-based protocell networks.Nature chemistry · 2024Article
- Target-dependent RNA polymerase as universal platform for gene expression control in response to intracellular molecules.Nature communications · 2023Article
- Advancing synthetic biology through cell-free protein synthesis.Computational and structural biotechnology journal · 2023Review
- Standardized excitable elements for scalable engineering of far-from-equilibrium chemical networks.Nature chemistry · 2022Article
- DNA-assisted selective electrofusion (DASE) ofNanoscale · 2022Article
- Signal-processing and adaptive prototissue formation in metabolic DNA protocells.Nature communications · 2022Article
- Expanding luciferase reporter systems for cell-free protein expression.Scientific reports · 2022Article
- A microfluidic optimal experimental design platform for forward design of cell-free genetic networks.Nature communications · 2022Article
- Article
- Cell-Free PURE System: Evolution and Achievements.Biodesign research · 2022Review
- Protocell arrays for simultaneous detection of diverse analytes.Nature communications · 2021Article
- Droplet Microfluidics for Tumor Drug-Related Studies and Programmable Artificial Cells.Global challenges (Hoboken, NJ) · 2021Review
- pH Feedback Lifecycles Programmed by Enzymatic Logic Gates Using Common Foods as Fuels.Angewandte Chemie (International ed. in English) · 2021Article
- Bioinspired Networks of Communicating Synthetic Protocells.Frontiers in molecular biosciences · 2021Review
- Higher-order structure of DNA determines its positioning in cell-size droplets under crowded conditions.PloS one · 2021Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Recent efforts in synthetic biology have shown the possibility of engineering distributed functions in populations of living cells, which requires the development of highly orthogonal, genetically encoded communication pathways. Cell-free transcription-translation (TXTL) reactions encapsulated in microcompartments enable prototyping of molecular communication channels and their integration into engineered genetic circuits by mimicking critical cell features, such as gene expression, cell size, and cell individuality within a community. In this review, we discuss the uses of cell-free transcription-translation reactions for the development of synthetic genetic circuits, with a special focus on the use of microcompartments supporting this reaction. We highlight several studies where molecular communication between non-living microcompartments and living cells have been successfully engineered.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.