Evidence map›Paper›PMID 30593904›Full record

ArticleNeuroImage2019

Maximising BOLD sensitivity through automated EPI protocol optimisation.

Steffen Volz, Martina F Callaghan, Oliver Josephs, Nikolaus Weiskopf

Abstract read
In one paragraph

Article in NeuroImage, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Steffen VolzDepartment of Neurophysics, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany; Wellcome Centre for Human Neuroimaging, UCL Institute of Neurology, University College London, London, UK. Electronic address: svolz@cbs.mpg.de.
Martina F CallaghanWellcome Centre for Human Neuroimaging, UCL Institute of Neurology, University College London, London, UK.
Oliver JosephsWellcome Centre for Human Neuroimaging, UCL Institute of Neurology, University College London, London, UK.
Nikolaus WeiskopfDepartment of Neurophysics, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany; Wellcome Centre for Human Neuroimaging, UCL Institute of Neurology, University College London, London, UK.

Funding

Wellcome Trust
6 · The paper itself

Abstract

Gradient echo echo-planar imaging (GE EPI) is used for most fMRI studies but can suffer substantially from image distortions and BOLD sensitivity (BS) loss due to susceptibility-induced magnetic field inhomogeneities. While there are various post-processing methods for correcting image distortions, signal dropouts cannot be recovered and therefore need to be addressed at the data acquisition stage. Common approaches for reducing susceptibility-related BS loss in selected brain areas are: z-shimming, inverting the phase encoding (PE) gradient polarity, optimizing the slice tilt and increasing spatial resolution. The optimization of these parameters can be based on atlases derived from multiple echo-planar imaging (EPI) acquisitions. However, this requires resource and time, which imposes a practical limitation on the range over which parameters can be optimised meaning that the chosen settings may still be sub-optimal. To address this issue, we have developed an automated method that can be used to optimize across a large parameter space. It is based on numerical signal simulations of the BS loss predicted by physical models informed by a large database of magnetic field (B

Indexed as

AdultBrainEcho-Planar ImagingHumansNeuroimagingReproducibility of Results

Identifiers

PMID30593904
PMCPMC6435104

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.