Evidence map›Paper›PMID 30593641›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2019

Isolation of HCV Neutralizing Antibodies by Yeast Display.

Zhen-Yong Keck, Yong Wang, Patrick Lau, Steven K H Foung

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Review
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  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Zhen-Yong KeckDepartment of Pathology, Stanford University School of Medicine, Stanford, CA, USA.
Yong WangDepartment of Pathology, Stanford University School of Medicine, Stanford, CA, USA.
Patrick LauDepartment of Pathology, Stanford University School of Medicine, Stanford, CA, USA.
Steven K H FoungDepartment of Pathology, Stanford University School of Medicine, Stanford, CA, USA. sfoung@stanford.edu.

Funding

Structure-Based Vaccine Design for Hepatits C VirusR01AI132213 · NIAID · UNIV OF MARYLAND, COLLEGE PARK · PI ANDRIANOV, ALEXANDER, FOUNG, STEVEN · 2017 to 2021
$6.0M
Project 2 - FranceU19AI123862 · NIAID · STANFORD UNIVERSITY · PI FOUNG, STEVEN · 2016 to 2020
$3.9M
Immunotherapeutics to prevent HCV reinfectionR41AI108024 · NIAID · INTEGRATED BIOTHERAPEUTICS, INC. · PI FOUNG, STEVEN, HOLTSBERG, FREDERICK WAYNE · 2013 to 2014
$600k
Structure-based HCV vaccine designR21AI126582 · NIAID · STANFORD UNIVERSITY · PI FOUNG, STEVEN, MARIUZZA, ROY A · 2016 to 2017
$440k
NIAID NIH HHS R01 AI132213NIAID NIH HHS R21 AI126582NIAID NIH HHS R41 AI108024NIAID NIH HHS U19 AI123862
6 · The paper itself

Abstract

Yeast surface display (YSD) enables efficient screening and selection of single chain variable fragments (scFvs) of heavy (V

Indexed as

Antibodies, NeutralizingB-LymphocytesCell Surface Display TechniquesCloning, MolecularEnzyme-Linked Immunosorbent AssayHepacivirusHepatitis CHepatitis C AntibodiesHumansPeptide LibrarySaccharomyces cerevisiaeSingle-Chain AntibodiesTransformation, GeneticAntibodies, NeutralizingHepatitis C AntibodiesPeptide LibrarySingle-Chain AntibodiesHepatitis C virusHuman monoclonal antibody isolationMutant antigen selectionVirus neutralizationYeast surface display

Identifiers

PMID30593641
PMCPMC6375674

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.