Evidence map›Paper›PMID 30593561›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2019

Constitutive Dicer1 phosphorylation accelerates metabolism and aging in vivo.

Neeraj K Aryal, Vinod Pant, Amanda R Wasylishen, Jan Parker-Thornburg, Laura Baseler, Adel K El-Naggar, Bin Liu, Awdhesh Kalia, Guillermina Lozano, Swathi Arur

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. MicroRNAs as Epigenetic Regulators of Obesity.Advances in experimental medicine and biology · 2024
    Review
  5. Article
  6. MicroRNA biogenesis pathway alterations in aging.Extracellular vesicles and circulating nucleic acids · 2023
    Review
  7. iScience · 2022
    Article
  8. Article
  9. Testicular aging, male fertility and beyond.Frontiers in endocrinology · 2022
    Review
  10. Review
  11. Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Neeraj K AryalDepartment of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
Vinod PantDepartment of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
Amanda R WasylishenDepartment of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
Jan Parker-ThornburgDepartment of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.ORCID 0000-0002-4464-8744
Laura BaselerDepartment of Veterinary Medicine and Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
Adel K El-NaggarDepartment of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
Bin LiuDepartment of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
Awdhesh KaliaSchool of Health Professions, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
Guillermina LozanoDepartment of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030; gglozano@mdanderson.org sarur@mdanderson.org.
Swathi ArurDepartment of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030; gglozano@mdanderson.org sarur@mdanderson.org.
The University of Texas MD Anderson Cancer Center · US

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Fabien Delerue · 1985 to 2026
$290.8M
Erk-mediated regulation of Dicer and Drosha function in C. elegansR01GM098200 · NIGMS · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI ARUR, SWATHI · 2011 to 2020
$3.3M
Instituting innovative CRISPR/Cas9 technology at an NCI Comprehensive Cancer Center transgenic facilityR50CA211121 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI PARKER-THORNBURG, JAN · 2017 to 2021
$1.2M
NCI NIH HHS P30 CA016672NCI NIH HHS R50 CA211121NIGMS NIH HHS R01 GM098200
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AgingDEAD-box RNA HelicasesHomozygoteMutation, MissenseRibonuclease IIIAmino Acid SubstitutionAnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsFemaleGene Knock-In TechniquesHEK293 CellsHumansMaleMicePhosphorylationCaenorhabditis elegans ProteinsDEAD-box RNA HelicasesDICER1 protein, humanDicer1 protein, mouseRibonuclease IIIagingERK signalinginfertilitymicroRNAmouse model

Identifiers

PMID30593561
PMCPMC6338878
OpenAlexW2906927248

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.