Evidence map›Paper›PMID 30593491›Full record

ArticleGenetics2019

Two Antagonistic Hippo Signaling Circuits Set the Division Plane at the Medial Position in the Ciliate

Yu-Yang Jiang, Wolfgang Maier, Ralf Baumeister, Ewa Joachimiak, Zheng Ruan, Natarajan Kannan, Diamond Clarke, Panagiota Louka, Mayukh Guha, Joseph Frankel and 1 more

Abstract read
In one paragraph

Article in Genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Anterior-posterior pattern formation in ciliates.The Journal of eukaryotic microbiology · 2022
    Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Polarity in Ciliate Models: From Cilia to Cell Architecture.Frontiers in cell and developmental biology · 2019
    Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yu-Yang JiangDepartment of Cellular Biology, University of Georgia, Athens, Georgia 30602.ORCID 0000-0002-0338-4252
Wolfgang MaierBio 3/Bioinformatics and Molecular Genetics, Faculty of Biology and ZBMZ, Faculty of Medicine, Albert-Ludwigs-University of Freiburg, 79104 Germany.
Ralf BaumeisterBio 3/Bioinformatics and Molecular Genetics, Faculty of Biology and ZBMZ, Faculty of Medicine, Albert-Ludwigs-University of Freiburg, 79104 Germany.
Ewa JoachimiakLaboratory of Cytoskeleton and Cilia Biology, Nencki Institute of Experimental Biology of Polish Academy of Sciences, Warsaw 02-093, Poland.ORCID 0000-0003-3185-7923
Zheng RuanInstitute of Bioinformatics, University of Georgia, Athens, Georgia 30602.ORCID 0000-0002-4412-4916
Natarajan KannanInstitute of Bioinformatics, University of Georgia, Athens, Georgia 30602.
Diamond ClarkeDepartment of Cellular Biology, University of Georgia, Athens, Georgia 30602.
Panagiota LoukaDepartment of Cellular Biology, University of Georgia, Athens, Georgia 30602.
Mayukh GuhaDepartment of Cellular Biology, University of Georgia, Athens, Georgia 30602.
Joseph FrankelDepartment of Biology, University of Iowa, Iowa 52242.
Jacek GaertigDepartment of Cellular Biology, University of Georgia, Athens, Georgia 30602 jgaertig@uga.edu.ORCID 0000-0003-4420-4630

Funding

Functional Annotation of Natural and Disease Variants in Tryosine KinasesR01GM114409 · NIGMS · UNIVERSITY OF GEORGIA · PI KANNAN, NATARAJAN · 2015 to 2020
$1.6M
Regulation of Cilium LengthR21HD092809 · NICHD · UNIVERSITY OF GEORGIA · PI GAERTIG, JACEK · 2017 to 2018
$413k
NICHD NIH HHS R21 HD092809NIGMS NIH HHS R01 GM114409
6 · The paper itself

Abstract

In a single cell, ciliates maintain a complex pattern of cortical organelles that are arranged along the anteroposterior and circumferential axes. The underlying molecular mechanisms of intracellular pattern formation in ciliates are largely unknown. Ciliates divide by tandem duplication, a process that remodels the parental cell into two daughters aligned head-to-tail. In the

Indexed as

Cell DivisionCell PolaritySignal TransductionProtein Serine-Threonine KinasesProtozoan ProteinsTetrahymenaProtein Serine-Threonine KinasesProtozoan ProteinsciliateLatspatternpolarityTetrahymena

Identifiers

PMID30593491
PMCPMC6366909

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.