Evidence map›Paper›PMID 30592756›Full record

ArticlePloS one2018

Pre-exposure prophylaxis for HIV prevention preferences among young adult African American men who have sex with men.

Rupa R Patel, John S Crane, Julia López, Philip A Chan, Albert Y Liu, Rubabin Tooba, Aimee S James

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 2 pooled it
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 2 syntheses or guidelines pooled it, 46 citations in OpenAlex.

  1. Pooled it
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  10. Exploring Willingness to Use Long-Acting Injectable PrEP Among Sexual and Gender Minoritized People Accessing Pharmacies.AIDS education and prevention : official publication of the International Society for AIDS Education · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Rupa R PatelDivision of Infectious Diseases, Washington University in St. Louis, St. Louis, Missouri, United States of America.ORCID 0000-0002-0329-7036
John S CraneDivision of Infectious Diseases, Washington University in St. Louis, St. Louis, Missouri, United States of America.
Julia LópezDepartment of Obstetrics and Gynecology, Washington University in St. Louis, St. Louis, Missouri, United States of America.ORCID 0000-0002-8197-002X
Philip A ChanDivision of Infectious Diseases, Brown University, Providence, Rhode Island, United States of America.
Albert Y LiuDepartment of Medicine, University of California San Francisco, San Francisco, California, United States of America.ORCID 0000-0003-0320-823X
Rubabin ToobaWashington University School of Medicine, Washington University in St. Louis, St. Louis, Missouri, United States of America.
Aimee S JamesDivision of Public Health Sciences, Washington University in St. Louis, St. Louis, Missouri, United States of America.
Washington University in St. Louis · USBrown University · USUniversity of California, San Francisco · US

Funding

WU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8M
Washington University Institute of Clinical and Translational SciencesUL1TR000448 · NCATS · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2012 to 2016
$41.4M
Washington University Institute of Clinical and Translational Sciences (KL2) KL2TR002346 · NCATS · WASHINGTON UNIVERSITY · PI Dominic N Reeds · 2017 to 2026
$14.0M
Washington University Institute of Clinical and Translational SciencesKL2TR000450 · NCATS · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2012 to 2016
$8.8M
The Brown Initiative in HIV and AIDS Clinical Research for Minority CommunitiesR25MH083620 · NIMH · MIRIAM HOSPITAL · PI NUNN, AMY STEWART · 2008 to 2025
$3.7M
Characterizing the HIV pre-exposure prophylaxis care continuum for African American and Hispanic/Latino men who have sex with menR01MH114657 · NIMH · MIRIAM HOSPITAL · PI CHAN, PHILIP ANDREW, NUNN, AMY STEWART · 2017 to 2021
$3.4M
NCATS NIH HHS KL2 TR000450NCATS NIH HHS KL2 TR002346NCATS NIH HHS UL1 TR000448NCATS NIH HHS UL1 TR002345NIMH NIH HHS R01 MH114657NIMH NIH HHS R25 MH083620
6 · The paper itself

Abstract

Pre-exposure prophylaxis (PrEP) is effective in preventing HIV infections among men who have sex with men (MSM). PrEP uptake and adherence remain low and product preferences are unknown, especially among young African American MSM who are most at-risk. We conducted 26 qualitative interviews from 2014-2016 among young adult HIV-negative African American MSM regarding PrEP product preferences in Missouri. While the pill and injectable were most liked of all modalities, about a quarter preferred rectal products or patches. Most participants preferred a long-acting injectable (LAI) to daily oral pills due to better medication adherence and a dislike for taking pills. Many participants preferred daily oral pills to on-demand oral PrEP due to the inability to predict sex and the perception that insufficient time or medication would not achieve HIV protection with on-demand. A fear of needles and the perception that there would not be therapeutic levels for a long duration were concerns with injectable PrEP. Study findings highlight the need for a range of prevention options for African American MSM and can inform PrEP product development as well as dissemination and implementation efforts.

Indexed as

Administration, OralAdultAnti-HIV AgentsBlack or African AmericanDrug MonitoringHIV InfectionsHumansMaleMissouriPatient PreferencePre-Exposure ProphylaxisSexual and Gender MinoritiesTime FactorsYoung AdultAnti-HIV Agents

Identifiers

PMID30592756
PMCPMC6310267
OpenAlexW2907671687

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.