ArticlePloS one2018
NPR1 paralogs of Arabidopsis and their role in salicylic acid perception.
Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 66 citations in OpenAlex.
- Review
- Towards an integrated molecular understanding of plant hormones.Journal of integrative plant biology · 2026Review
- Genetic suppressors of the growth-immunity trade-off in the Arabidopsis salicylic acid-accumulating dmr6 dlo1 mutant.The Plant journal : for cell and molecular biology · 2025Article
- Characterization and expression patterns of theJournal of genetics · 2025Article
- NPR1 promotes blue light-induced plant photomorphogenesis by ubiquitinating and degrading PIF4.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- The Emerging Role ofPlants (Basel, Switzerland) · 2024Review
- The expression of the NPR1-dependent defense response pathway genes in Persea americana (Mill.) following infection with Phytophthora cinnamomi.BMC plant biology · 2023Article
- Advances in understanding the mechanism of resistance to anthracnose and induced defence response in tea plants.Molecular plant pathology · 2023Review
- Seeing is believing: Understanding functions of NPR1 and its paralogs in plant immunity through cellular and structural analyses.Current opinion in plant biology · 2023Review
- Article
- Endogenous salicylic acid suppresses de novo root regeneration from leaf explants.PLoS genetics · 2023Article
- Overexpression ofFrontiers in plant science · 2022Article
- Comparison of the pathway structures influencing the temporal response of salicylate and jasmonate defence hormones inFrontiers in plant science · 2022Review
- Oxicam-type non-steroidal anti-inflammatory drugs inhibit NPR1-mediated salicylic acid pathway.Nature communications · 2021Article
- SA-Mediated Regulation and Control of Abiotic Stress Tolerance in Rice.International journal of molecular sciences · 2021Review
- Plant Allelochemicals as Sources of Insecticides.Insects · 2021Review
- Article
- Plant hairy roots enable high throughput identification of antimicrobials against Candidatus Liberibacter spp.Nature communications · 2020Article
- Unravelling Cotton Nonexpressor of Pathogenesis-Related 1(NPR1)-Like Genes Family: Evolutionary Analysis and Putative Role in Fiber Development and Defense Pathway.Plants (Basel, Switzerland) · 2020Article
- Directing Trophic Divergence in Plant-Pathogen Interactions: Antagonistic Phytohormones With NO Doubt?Frontiers in plant science · 2020Review
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Salicylic acid (SA) is responsible for certain plant defence responses and NON EXPRESSER OF PATHOGENESIS RELATED 1 (NPR1) is the master regulator of SA perception. In Arabidopsis thaliana there are five paralogs of NPR1. In this work we tested the role of these paralogs in SA perception by generating combinations of mutants and transgenics. NPR2 was the only paralog able to partially complement an npr1 mutant. The null npr2 reduces SA perception in combination with npr1 or other paralogs. NPR2 and NPR1 interacted in all the conditions tested, and NPR2 also interacted with other SA-related proteins as NPR1 does. The remaining paralogs behaved differently in SA perception, depending on the genetic background, and the expression of some of the genes induced by SA in an npr1 background was affected by the presence of the paralogs. NPR2 fits all the requirements of an SA receptor while the remaining paralogs also work as SA receptors with a strong hierarchy. According to the data presented here, the closer the gene is to NPR1, the more relevant its role in SA perception.
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