Evidence map›Paper›PMID 30592635›Full record

Trial reportJournal of child and adolescent psychopharmacology2019

Attendance and Engagement in Parent Training Predict Child Behavioral Outcomes in Children Pharmacologically Treated for Attention-Deficit/Hyperactivity Disorder and Severe Aggression.

Heather M Joseph, Cristan Farmer, Heidi Kipp, David Kolko, Michael Aman, James McGinley, L Eugene Arnold, Kenneth D Gadow, Robert L Findling, Brooke S G Molina

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of child and adolescent psychopharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

Heather M Joseph1 Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania.
Cristan Farmer2 Office of the Clinical Director, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland.
Heidi Kipp1 Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania.
David Kolko1 Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania.
Michael Aman3 Department of Psychiatry, The Ohio State University, Columbus, Ohio.
James McGinley4 Vector Psychometric Group, LLC, Chapel Hill, North Carolina.
L Eugene Arnold3 Department of Psychiatry, The Ohio State University, Columbus, Ohio.
Kenneth D Gadow5 Department of Psychiatry, Stony Brook University, Stony Brook, New York.
Robert L Findling6 Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, Maryland.
Brooke S G Molina1 Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania.
University of Pittsburgh · USThe Ohio State University · USCarolina Institute for NanoMedicine · USJohns Hopkins University · USNational Institutes of Health · USStony Brook University · US

Funding

UNIVERSITY OF PITTSBURGH CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTE: BPCAUL1RR024153 · NCRR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2006 to 2011
$73.9M
University of Pittsburgh Clinical and Translational Science InstituteUL1TR000005 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2012 to 2015
$50.8M
World Trade Center Worker and Volunteer Medical Screening ProgramM01RR010710 · NCRR · STATE UNIVERSITY NEW YORK STONY BROOK · PI BAHOU, WADIE F · 1998 to 2009
$17.6M
CLINICAL RESEARCH TRAINING IN CHILD PSYCHIATRYT32MH018951 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI TINA R GOLDSTEIN · 1990 to 2026
$9.7M
The Ohio State University Center for Clinical and Translational Science (UL1)UL1TR000090 · NCATS · OHIO STATE UNIVERSITY · PI JACKSON, REBECCA D · 2012 to 2013
$7.9M
1/4-Stimulant and Risperidone for Youth with Severe Physical AggressionR01MH077907 · NIMH · OHIO STATE UNIVERSITY · PI AMAN, MICHAEL GEORGE · 2008 to 2011
$1.9M
3/4-Stimulant and Risperidone for Youth with Severe Physical AggressionR01MH077750 · NIMH · CASE WESTERN RESERVE UNIVERSITY · PI MCNAMARA, NORA · 2008 to 2011
$1.6M
2/4-Stimulant and Risperidone for Youth with Severe Physical AggressionR01MH077676 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MOLINA, BROOKE S.G. · 2008 to 2011
$1.6M
4/4-Stimulant and Risperidone for Youth with Severe Physical AggressionR01MH077997 · NIMH · STATE UNIVERSITY NEW YORK STONY BROOK · PI GADOW, KENNETH D · 2008 to 2011
$1.5M
NCATS NIH HHS UL1 TR000005NCATS NIH HHS UL1 TR000090NCRR NIH HHS M01 RR010710NCRR NIH HHS UL1 RR024153NIMH NIH HHS R01 MH077676NIMH NIH HHS R01 MH077750NIMH NIH HHS R01 MH077907NIMH NIH HHS R01 MH077997NIMH NIH HHS T32 MH018951
6 · The paper itself

Abstract

objectivesWe examined the association of parent training (PT)-related factors with therapeutic success in the Treatment of Severe Childhood Aggression (TOSCA) study. Our aims were (1) to evaluate demographic and clinical characteristics as predictors of parent attendance and engagement in PT and (2) to examine the associations of parent attendance and engagement in PT with study-targeted child behavior outcomes (i.e., attention-deficit/hyperactivity disorder [ADHD] and disruptive behavior symptoms). TOSCA was a randomized clinical trial evaluating the effect of placebo versus risperidone when added to PT and psychostimulant for childhood ADHD with severe aggression.

methodsData for 167 parents and children 6-12 years old with ADHD, oppositional defiant disorder (ODD) or conduct disorder, and severe physical aggression were examined. Analyses used generalized linear models.

resultsMost parents (72%) attended seven or more of nine sessions. The average parental engagement, that is, the percentage of PT elements fully achieved across participants and sessions, was 85%. The average therapist rating of goal completion was 92%. Parents of non-white and/or Hispanic children (p = 0.01) and children with lower intelligence quotient (p = 0.02) had lower PT attendance; parents with lower family incomes (p = 0.01) were less engaged. Attendance and engagement predicted better scores on the primary child behavior outcomes of disruptive behavior (Nisonger Child Behavior Rating Form Disruptive Behavior Total) and ADHD and ODD symptoms, adjusting for baseline severity.

conclusionsWhen the clinical picture is sufficiently severe to warrant prescribing an atypical antipsychotic, PT is feasible for families of children with ADHD and co-occurring severe aggression. The promotion of attendance and engagement in PT is important to enhance clinical outcomes among this challenging population. Methods for overcoming barriers to participation in PT deserve vigorous investigation, particularly for those with low family income, non-white race, Hispanic ethnicity, or when children have lower cognitive level.

Indexed as

AggressionAntipsychotic AgentsAttention Deficit and Disruptive Behavior DisordersAttention Deficit Disorder with HyperactivityCentral Nervous System StimulantsChildCombined Modality TherapyConduct DisorderDrug Therapy, CombinationFemaleHumansMaleParent-Child RelationsParentsRisperidoneSeverity of Illness IndexAntipsychotic AgentsCentral Nervous System StimulantsRisperidoneADHDaggressionantipsychoticparent trainingstimulant

Identifiers

PMID30592635
PMCPMC6442260
OpenAlexW2907141462

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.