Evidence map›Paper›PMID 30592363›Full record

ArticleEuropean journal of heart failure2019

Optimal haemodynamics during left ventricular assist device support are associated with reduced haemocompatibility-related adverse events.

Teruhiko Imamura, Ann Nguyen, Gene Kim, Jayant Raikhelkar, Nitasha Sarswat, Sara Kalantari, Bryan Smith, Colleen Juricek, Daniel Rodgers, Takeyoshi Ota and 4 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of heart failure, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it, 89 citations in OpenAlex.

  1. Pooled it
  2. Haemolytic injury and cardiovascular disease.Nature reviews. Cardiology · 2026
    Review
  3. Article
  4. Fibrosis 4 Index Predicts Haemocompatibility-Related Adverse Events in Patients Using Left Ventricular Assist Devices.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2025
    Article
  5. Article
  6. Hemodynamic parameters at rest predicting exercise capacity in patients supported with left ventricular assist device.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2024
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Teruhiko ImamuraDepartment of Medicine, University of Chicago Medical Center, Chicago, IL, USA.
Ann NguyenDepartment of Medicine, University of Chicago Medical Center, Chicago, IL, USA.
Gene KimDepartment of Medicine, University of Chicago Medical Center, Chicago, IL, USA.
Jayant RaikhelkarDepartment of Medicine, University of Chicago Medical Center, Chicago, IL, USA.
Nitasha SarswatDepartment of Medicine, University of Chicago Medical Center, Chicago, IL, USA.
Sara KalantariDepartment of Medicine, University of Chicago Medical Center, Chicago, IL, USA.
Bryan SmithDepartment of Medicine, University of Chicago Medical Center, Chicago, IL, USA.
Colleen JuricekDepartment of Surgery, University of Chicago Medical Center, Chicago, IL, USA.
Daniel RodgersDepartment of Medicine, University of Chicago Medical Center, Chicago, IL, USA.
Takeyoshi OtaDepartment of Surgery, University of Chicago Medical Center, Chicago, IL, USA.
Tae SongDepartment of Surgery, University of Chicago Medical Center, Chicago, IL, USA.
Valluvan JeevanandamDepartment of Surgery, University of Chicago Medical Center, Chicago, IL, USA.
Gabriel SayerDepartment of Medicine, University of Chicago Medical Center, Chicago, IL, USA.
Nir UrielDepartment of Medicine, University of Chicago Medical Center, Chicago, IL, USA.
University of Chicago Medical Center · US

Funding

MULTIDISCIPLINARY CARDIAC SCIENCEST32HL007381 · NHLBI · UNIVERSITY OF CHICAGO · PI JEANNE M DECARA, Yoav Gilad · 1985 to 2026
$12.5M
NHLBI NIH HHS T32 HL007381
6 · The paper itself

Abstract

aimsLeft ventricular assist device (LVAD) therapy improves the haemodynamics of advanced heart failure patients. However, it is unknown whether haemodynamic optimization improves haemocompatibility-related adverse events (HRAEs). This study aimed to assess HRAEs in patients with optimized haemodynamics. METHODS AND

resultsEighty-three outpatients [aged 61 (53-67) years, 50 male] underwent a haemodynamic ramp test at 253 (95-652) days after LVAD implantation, and 51 (61%) had optimized haemodynamics (defined as central venous pressure < 12 mmHg, pulmonary artery wedge pressure < 18 mmHg, cardiac index > 2.2 L/min/m

conclusionLeft ventricular assist device patients in whom haemodynamics can be optimized had greater freedom from HRAEs compared to those without optimized haemodynamics.

Indexed as

HemodynamicsAgedAssisted CirculationCardiac CatheterizationCardiac OutputCentral Venous PressureEquipment FailureFemaleHeart-Assist DevicesHeart FailureHemorrhageHumansMaleMiddle AgedProportional Hazards ModelsPulmonary Wedge PressureHeart failureHeartMateRamp

Identifiers

PMID30592363
PMCPMC7147872
OpenAlexW2907136111

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.