Evidence map›Paper›PMID 30592237›Full record

ArticleOphthalmic epidemiology2019

Optimising age adjustment of trichiasis prevalence estimates using data from 162 standardised surveys from seven regions of Ethiopia.

Colin K Macleod, Travis C Porco, Michael Dejene, Oumer Shafi, Biruck Kebede, Nebiyu Negussu, Berhanu Bero, Sadik Taju, Yilikal Adamu, Kassahun Negash and 7 more

Abstract read
In one paragraph

Article in Ophthalmic epidemiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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3citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

17 authors.

Colin K Macleoda Clinical Research Department , London School of Hygiene & Tropical Medicine , London , UK.
Travis C Porcob Francis I. Proctor Foundation, Department of Ophthalmology , University of California, San Francisco , San Francisco , USA.
Michael Dejened Michael Dejene Public Health Consultancy Services , Addis Ababa , Ethiopia.
Oumer Shafie Federal Ministry of Health , Addis Ababa , Ethiopia.
Biruck Kebedee Federal Ministry of Health , Addis Ababa , Ethiopia.
Nebiyu Negussue Federal Ministry of Health , Addis Ababa , Ethiopia.
Berhanu Berof The Fred Hollows Foundation Ethiopia , Addis Ababa , Ethiopia.
Sadik Tajug Department of Ophthalmology , Addis Ababa University , Addis Ababa , Ethiopia.
Yilikal Adamug Department of Ophthalmology , Addis Ababa University , Addis Ababa , Ethiopia.
Kassahun Negashh AMREF Health Africa Ethiopia , Addis Ababa , Ethiopia.
Tesfaye Haileselassiei ORBIS International , Addis Ababa , Ethiopia.
John Riangj Gambella Regional Health Bureau , Gambella , Ethiopia.
Ahmed Badeik Department of Disease Prevention , Somali Regional State Health Bureau , Jigjiga , Ethiopia.
Ana Bakhtiaril Task Force for Global Health , Decatur , Georgia , USA.
Rebecca Willisl Task Force for Global Health , Decatur , Georgia , USA.
Robin L Baileya Clinical Research Department , London School of Hygiene & Tropical Medicine , London , UK.
Anthony W Solomona Clinical Research Department , London School of Hygiene & Tropical Medicine , London , UK.

Funding

Wellcome TrustWellcome Trust 098521World Health Organization 001
6 · The paper itself

Abstract

purposeThe prevalence of trichiasis is higher in females and increases markedly with age. Surveys carried out in the daytime, particularly in developing countries, are prone to find older individuals and females at home at the time of the survey. Population-level trichiasis estimates should adjust sample proportions to reflect the demographic breakdown of the population, although the most accurate method of doing this is unclear.

methodsHaving obtained data from 162 surveys carried out in Ethiopia as part of the Global Trachoma Mapping Project from 2012 to 2015, we used internal validation with both Brier and Logarithmic forecast scoring to test stratification models to identify those models with the highest predictive accuracy. Selection of partitions was undertaken by both simple random sampling (SRS) and cluster sampling (CS) over 8192 selections.

resultsA total of 4529 (1.9%) cases of trichiasis were identified from 241,139 individuals aged ≥15 years from a total of 4210 kebeles and 122,090 households visited. Overall, the binning method using 5-year bands from age 15 to 69 years, with coarser binning in 20-year age-bands above this age, provided the best predictive accuracy, in both SRS and CS methodologies and for both the Brier and Logarithmic scoring rules.

conclusionThe greatest predictive accuracy for trichiasis estimates was found by adjusting for sex and in 5-year age-bands from the age of 15 to 69 years and in 20-year age-bands in those aged 70 years and greater. Trichiasis surveys attempting to make population-level inferences should use this method to optimise surgery backlog estimates.

Indexed as

AdolescentAdultAgedCluster AnalysisEthiopiaFemaleHumansMaleMiddle AgedPopulation SurveillancePrevalenceTrichiasisYoung AdultGlobal Trachoma Mapping Projectpopulation-based prevalence surveyTrachomatrichiasis

Identifiers

PMID30592237
PMCPMC6532728

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