Evidence map›Paper›PMID 30591956›Full record

ArticleJournal of the Endocrine Society2019

Unilateral Adrenalectomy Could Be a Valid Option for Primary Nodular Adrenal Disease: Evidence From Twins.

Aglaia Kyrilli, Maria Lytrivi, Marie Sylvie Bouquegneau, Pieter Demetter, Valerio Lucidi, Camilo Garcia, Rodrigo Moreno-Reyes, Antoine Tabarin, Bernard Corvilain, Natacha Driessens

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of the Endocrine Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. NovelFrontiers in endocrinology · 2024
    Review
  4. Adrenal Cushing's syndrome in children.Frontiers in endocrinology · 2023
    Review
  5. Treatment of Primary Pigmented Nodular Adrenocortical Disease.Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme · 2022
    Review
  6. Article
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Aglaia KyrilliDivision of Endocrinology, Hôpital Erasme, Brussels, Belgium.ORCID 0000-0002-9896-4419
Maria LytriviDivision of Endocrinology, Hôpital Erasme, Brussels, Belgium.
Marie Sylvie BouquegneauDivision of Endocrinology, CHU Ambroise Pare, Mons, Belgium.ORCID 0000-0002-3544-2170
Pieter DemetterDivision of Anatomopathology, Hôpital Erasme, Brussels, Belgium.
Valerio LucidiDivision of Digestive Surgery, Hôpital Erasme, Brussels, Belgium.
Camilo GarciaDivision of Nuclear Medicine, Bordet Institut, Brussels, Belgium.
Rodrigo Moreno-ReyesDivision of Nuclear Medicine, Hôpital Erasme, Brussels, Belgium.
Antoine TabarinDivision of Endocrinology, CHU de Bordeaux, France.
Bernard CorvilainDivision of Endocrinology, Hôpital Erasme, Brussels, Belgium.
Natacha DriessensDivision of Endocrinology, Hôpital Erasme, Brussels, Belgium.ORCID 0000-0002-5992-2486
Erasmus Hospital · BECentre Hospitalier Universitaire de Bordeaux · FRCHU Ambroise Paré · BEInstitut Jules Bordet · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary pigmented nodular adrenal disease (PPNAD) accounts for <1% of ACTH-independent Cushing syndrome. We describe the case of twin female patients with PPNAD who both had sustainable disease control after unilateral adrenalectomy, which corroborates current evidence in favor of unilateral adrenalectomy for a subset of patients with PPNAD. Patient A presented with a 10-kg weight gain over the past year and facial plethora. Diagnostic evaluation revealed abolition of normal cortisol rhythm with suppressed ACTH levels, normal adrenal CT and MRI imaging and a slightly left-predominant adrenal uptake on

Indexed as

Cushing syndromePPNADtwinsunilateral adrenalectomy

Identifiers

PMID30591956
PMCPMC6302904
OpenAlexW2898411712

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.