ReviewJournal of bone oncology2018
Systematic review: Incidence, risk factors, survival and treatment of bone metastases from colorectal cancer.
Review in Journal of bone oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
36 citing papers in PubMed, 56 citations in OpenAlex.
- Atypical bone and synovial metastases from colorectal adenocarcinoma: A case report.Radiology case reports · 2026Article
- Acral metastasis of colonic cancer: A case report.Qatar medical journal · 2026Article
- Bone metastasis in colorectal cancer: Pathophysiology, prognostic factors, survival outcomes, and treatment strategies - A comprehensive review.Journal of bone oncology · 2025Review
- Article
- Predicting bone metastasis risk of colorectal tumors using radiomics and deep learning ViT model.Journal of bone oncology · 2025Article
- Risk factors for organ-space surgical site infections after minimally invasive rectal cancer surgery: a retrospective cohort study.BMC gastroenterology · 2025Article
- Incidence and Prevalence of Bone Metastases in Different Solid Tumors Determined by Natural Language Processing of CT Reports.Cancers · 2025Article
- Recognition of the novel items for prediction of bone metastasis in colorectal cancer.Frontiers in oncology · 2025Article
- Case Report: Is the isolated bone change in advanced colorectal cancer necessarily malignant metastasis?Frontiers in oncology · 2025Article
- Exploring the correlation between Tom1L1 and the efficacy of neoadjuvant chemotherapy for locally progressive mid-low rectal cancer.BMC cancer · 2024Article
- A nomogram predicting the risk of extrathoracic metastasis at initial diagnosis of TTranslational lung cancer research · 2024Article
- Incidence, Risk Factors, and Survival of Bone Metastases and Skeletal-Related Events in Melanoma Patients: A Systematic Review and Quality Assessment of 29 Studies.Journal of bone oncology · 2024Review
- Misdiagnosis of multiple myeloma as postoperative bone metastasis of rectal cancer: A case report and literature review.Oncology letters · 2024Article
- Distal Fibular Metastasis of Colorectal Carcinoma: A Case Report.Orthopedic reviews · 2024Article
- Prognostic impact of colorectal cancer patients with bone metastases: a single-center experience.Updates in surgery · 2023Article
- Prevalence and prognosis of bone metastases in common solid cancers at initial diagnosis: a population-based study.BMJ open · 2023Article
- Differential Perspectives by Specialty on Oligometastatic Colorectal Cancer: A Korean Oligometastasis Working Group's Comparative Survey Study.Cancer research and treatment · 2023Article
- Primary Tumor Resection Plus Chemotherapy versus Chemotherapy Alone for Colorectal Cancer Patients with Synchronous Bone Metastasis.Medicina (Kaunas, Lithuania) · 2023Article
- Nursing care and management of adverse events for patients with BRAFSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023Review
- Operable hepatitis B virus-related hepatocellular carcinoma: gut microbiota profile of patients at different ages.Annals of translational medicine · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBones are not considered a frequent metastatic site in patients with colorectal cancer (CRC). The purpose of the present study was to determine the incidence of bone metastases (BM) in CRC, to identify possible risk factors for BM, survival after BM, and effect of treatment of BM including antiresorptive treatment. MATERIAL AND
methodsA computer-based literature search was carried out using PubMed and EMBASE.
resultsWe included 29 studies. One randomized placebo controlled trial (RCT) study, two autopsy studies, five register studies, and twenty retrospective cohort studies. The studies described different cohorts making direct comparison difficult. Three studies analysed the effect of different treatments for BM including one RCT study.
conclusionThe incidence of bone metastases was 3-7% in patients with CRC, and it was not possible to detect an increase in incidence over time. The most well established risk factors for BM are rectal cancer, having lymph node invasion at surgery of primary tumor, and lung metastases at any time. Other risk factors such as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.