Evidence map›Paper›PMID 30591802›Full record

ArticleSaudi journal of biological sciences2018

Association of ADAM33 gene polymorphisms with asthma in Mongolian and Han groups in Inner Mongolia.

Shufen Zhu, Pengfei Li, Hong Suo, Jingsheng Dong, Liying Cui

Open access · hybridAbstract read
In one paragraph

Article in Saudi journal of biological sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Shufen ZhuAffiliated Hospital of Inner Mongolia Medical University, Hohhot 010011, China.
Pengfei LiInner Mongolia Autonomous Region People's Hospital, Hohhot 010011, China.
Hong SuoAffiliated Hospital of Inner Mongolia Medical University, Hohhot 010011, China.
Jingsheng DongAffiliated Hospital of Inner Mongolia Medical University, Hohhot 010011, China.
Liying CuiAffiliated Hospital of Inner Mongolia Medical University, Hohhot 010011, China.
Inner Mongolia Medical University · CNInner Mongolia People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polymorphisms in the gene encoding for A disintegrin and metalloprotease 33 (ADAM33) are closely associated with the risk of bronchial asthma attacks in different populations. We collected blood samples from 248 asthma patients - 130 of the Han ethnic group and 118 of the Mongolian ethnic group - living in the Inner Mongolia region of China, and analyzed the single nuclear polymorphisms (SNPs) of the T1, T2 and V4 loci of the ADAM33 gene using PCR-RFLP (restriction fragment length polymorphism). In addition, we also tested 256 healthy controls (134 and 122 from the Han and Mongolian ethnic groups respectively) for the same SNPs. Three genotypes of the T1, T2 and V4 loci were predominantly detected: while polymorphisms in the T1 locus were significantly associated with asthma risk in both Mongolian and Han ethnicities (

Indexed as

ADAM33AsthmaGene polymorphismHan groupMongolian groupPCR-RFLP

Identifiers

PMID30591802
PMCPMC6303168
OpenAlexW2885404110

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.