ArticleInternational journal of environmental research and public health2018
Combined Influence of Depression and Physical Frailty on Cognitive Impairment in Patients with Heart Failure.
Article in International journal of environmental research and public health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.
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Who cites it
10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.
- Prevalence and associated factors of cognitive frailty in older adults with heart failure: a systematic review and meta-analysis.Frontiers in public health · 2026Pooled it
- Brain Imaging Changes and Related Risk Factors of Cognitive Impairment in Patients With Heart Failure.Frontiers in cardiovascular medicine · 2021Pooled it
- Prevalence of cognitive frailty and its associated factors in a population of Iranian older adults.Aging clinical and experimental research · 2024Article
- Cognitive impairment in patients with heart failure: molecular mechanism and therapy.Heart failure reviews · 2023Review
- Importance analysis of psychosociological variables in frailty syndrome in heart failure patients using machine learning approach.Scientific reports · 2023Article
- Association of sleep duration and physical frailty with cognitive function in older patients with coexisting atrial fibrillation and heart failure.Nursing open · 2023Article
- Body mass index among elderly population and its association with neurological and musculoskeletal diseases in Aseer, Saudi Arabia.Journal of family medicine and primary care · 2022Article
- Risk Factors of Metabolic Syndrome Among Patients Receiving Antipsychotics: A Retrospective Study.Community mental health journal · 2020Article
- Integrating assessment of cognitive status in elderly cardiovascular care.Clinical cardiology · 2020Review
- The Association Between Body Mass Index and Comorbidity, Quality of Life, and Cognitive Function in the Elderly Population.International journal of community based nursing and midwifery · 2020Article
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cognitive impairment is a prevalent condition and important barrier to self-care behaviors in patients with heart failure (HF). HF patients with depression or physical frailty are more likely to have reduced cognitive function. However, it remains unclear if combined depression and physical frailty increased the risk of cognitive impairments among HF populations. This study aimed to identify the influence of combined depression and physical frailty on cognitive impairments in HF. This cross-sectional study was included 289 patients with HF in outpatient cardiology clinics at a tertiary care university hospital in Cheonan, South Korea. We obtained patients' characteristics including depression, physical frailty, and cognitive function with Korean validated tools using a face-to-face interview. The prevalence rate of cognitive impairment was approximately 27.3% in HF outpatients. We found that the combined influence of depression and physical frailty increased the risk of cognitive impairments in both unadjusted (odds ratio (OR) 4.360; 95% confidence interval (CI) (2.113, 8.994)) and adjusted models (OR 3.545; 95% CI (1.448, 8.681)). Our findings highlight that healthcare professionals need to be more aware of the vulnerable population who suffer from both depression and physical frailty at the same time. Future prospective studies should examine the causal relationships among depression, physical frailty and cognitive impairment during the HF illness trajectories.
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