Evidence map›Paper›PMID 30591570›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2019

Regulation of acetate metabolism and coordination with the TCA cycle via a processed small RNA.

François De Mets, Laurence Van Melderen, Susan Gottesman

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
6.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 100 citations in OpenAlex.

  1. Article
  2. Review
  3. Overcoming phagocytosis resistance of hypervirulentMicrobial cell (Graz, Austria) · 2026
    Article
  4. Origin and adaptive evolutionary trajectory of the 3' UTR-derived sRNA UhpU in Enterobacteriaceae.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  5. Article
  6. Review
  7. Enhancing3 Biotech · 2025
    Article
  8. Article
  9. Article
  10. An RNase III-processed sRNA coordinates sialic acid metabolism ofProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. RpoS and the bacterial general stress response.Microbiology and molecular biology reviews : MMBR · 2024
    Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

François De MetsCellular and Molecular Microbiology, Faculté des Sciences, Université Libre de Bruxelles, B-6041 Gosselies, Belgium.
Laurence Van MelderenCellular and Molecular Microbiology, Faculté des Sciences, Université Libre de Bruxelles, B-6041 Gosselies, Belgium.
Susan GottesmanLaboratory of Molecular Biology, National Cancer Institute, Bethesda, MD 20892-5430 gottesms@mail.nih.gov.ORCID 0000-0002-7792-1284
Université Libre de Bruxelles · BENational Cancer Institute · US

Funding

Bacterial Functions Involved in Cell Growth ControlZIABC008714 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI GOTTESMAN, SUSAN · 2009 to 2025
$20.3M
Intramural NIH HHS ZIA BC008714
6 · The paper itself

Abstract

Bacterial regulatory small RNAs act as crucial regulators in central carbon metabolism by modulating translation initiation and degradation of target mRNAs in metabolic pathways. Here, we demonstrate that a noncoding small RNA, SdhX, is produced by RNase E-dependent processing from the 3'UTR of the

Indexed as

AcetatesCitric Acid CycleDrug Resistance, BacterialEscherichia coli K12Escherichia coli ProteinsHydroxyureaOperonRNA, BacterialRNA, Small UntranslatedAcetatesEscherichia coli ProteinsHydroxyureaRNA, BacterialRNA, Small Untranslatedacetate kinaseacetyl-phosphateHfqhydroxyureaRybD

Identifiers

PMID30591570
PMCPMC6338826
OpenAlexW2907374855

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.