Evidence map›Paper›PMID 30591056›Full record

ArticleRadiation oncology (London, England)2018

DPM as a radiation transport engine for PRIMO.

Miguel Rodriguez, Josep Sempau, Christian Bäumer, Beate Timmermann, Lorenzo Brualla

Abstract read
In one paragraph

Article in Radiation oncology (London, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. PRIMO Monte Carlo software as a tool for commissioning of an external beam radiotherapy treatment planning system.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2023
    Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Miguel RodriguezCentro Médico Paitilla, Calle 53 y ave. Balboa, Panama City, Panama.
Josep SempauUniversitat Politècnica de Catalunya, Diagonal 647, Barcelona, E-08028, Spain.
Christian BäumerWest German Proton Therapy Centre Essen (WPE), Hufelandstraße 55, Essen, D-45147, Germany.
Beate TimmermannWest German Proton Therapy Centre Essen (WPE), Hufelandstraße 55, Essen, D-45147, Germany.
Lorenzo BruallaWest German Proton Therapy Centre Essen (WPE), Hufelandstraße 55, Essen, D-45147, Germany. lorenzo.brualla@uni-duisburg-essen.de.ORCID http://orcid.org/0000-0003-3385-9623

Funding

Deutsche Forschungsgemeinschaft BR 4043/3-1H2020 EJP Concert 003-2017-PODIUMOpen Access Publication Fund of the University of Duisburg-Essen N/ASpanish Networking Research Center CIBER-BBN N/A
6 · The paper itself

Abstract

backgroundPRIMO is a dose verification system based on the general-purpose Monte Carlo radiation transport code PENELOPE, which implements an accurate physics model of the interaction cross sections and the radiation transport process but with low computational efficiency as compared with fast Monte Carlo codes. One of these fast Monte Carlo codes is the Dose Planning Method (DPM). The purpose of this work is to describe the adaptation of DPM as an alternative PRIMO computation engine, to validate its performance against PENELOPE and to validate it for some specific cases.

methodsDPM was parallelized and modified to perform radiation transport in quadric geometries, which are used to describe linacs, thus allowing the simulation of dynamic treatments. To benchmark the new code versus PENELOPE, both in terms of accuracy of results and simulation time, several tests were performed, namely, irradiation of a multi-layer phantom, irradiation of a water phantom using a collimating pattern defined by the multileaf collimator (MLC), and four clinical cases. The gamma index, with passing criteria of 1 mm/1%, was used to compare the absorbed dose distributions. Clinical cases were compared using a 3-D gamma analysis.

resultsThe percentage of voxels passing the gamma criteria always exceeded 99% for the phantom cases, with the exception of the transport through air, for which dose differences between DPM and PENELOPE were as large as 24%. The corresponding percentage for the clinical cases was larger than 99%. The speedup factor between DPM and PENELOPE ranged from 2.5 ×, for the simulation of the radiation transport through a MLC and the subsequent dose estimation in a water phantom, up to 11.8 × for a lung treatment. A further increase of the computational speed, up to 25 ×, can be obtained in the clinical cases when a voxel size of (2.5 mm)

conclusionsDPM has been incorporated as an efficient and accurate Monte Carlo engine for dose estimation in PRIMO. It allows the concatenated simulation of the patient-dependent part of the linac and the patient geometry in static and dynamic treatments. The discrepancy observed between DPM and PENELOPE, which is due to an artifact of the cross section interpolation algorithm for low energy electrons in air, does not affect the results in other materials.

Indexed as

Monte Carlo MethodPhantoms, ImagingAlgorithmsBrain NeoplasmsComputer SimulationHead and Neck NeoplasmsHumansLung NeoplasmsParticle AcceleratorsRadiotherapy DosageRadiotherapy, Intensity-ModulatedRadiotherapy Planning, Computer-AssistedSoftwareLinear acceleratorMonte CarloRadiation transport

Identifiers

PMID30591056
PMCPMC6307123

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.