ArticleBMC complementary and alternative medicine2018
Maoberry (Antidesma bunius) ameliorates oxidative stress and inflammation in cardiac tissues of rats fed a high-fat diet.
Article in BMC complementary and alternative medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 25 citations in OpenAlex.
- Effects of Environmental Temperature During Cultivation of Broccoli Microgreens on Hematological Parameters, Molecular Markers, and Myocardial Antioxidant Status in Swiss Mice.Food science & nutrition · 2026Article
- Lactiplantibacillus plantarum from Thai fermented pork with inulin ameliorates metabolic disturbances through proteomic mechanisms.Scientific reports · 2025Article
- Dietary Antioxidants and Natural Compounds in Preventing Thrombosis and Cardiovascular Disease.International journal of molecular sciences · 2024Review
- Assessing the therapeutic potential of long-chain isomaltooligosaccharides in diabetic and hyperlipidemic rats.Diabetology & metabolic syndrome · 2024Article
- High Fructose and High Fat Diet Impair Different Types of Memory through Oxidative Stress in a Sex- and Hormone-Dependent Manner.Metabolites · 2022Article
- Screening of potential tropical fruits in protecting endothelial dysfunctionFood & nutrition research · 2021Article
- Antioxidant Food Components for the Prevention and Treatment of Cardiovascular Diseases: Effects, Mechanisms, and Clinical Studies.Oxidative medicine and cellular longevity · 2021Review
- Cafeteria Diet-Induced Metabolic and Cardiovascular Changes in Rats: The Role ofEvidence-based complementary and alternative medicine : eCAM · 2021Article
- Mechanisms of Chronic Metabolic Stress in Arrhythmias.Antioxidants (Basel, Switzerland) · 2020Review
- Phenolic Profile, Antioxidant Activity, and Anti-obesogenic Bioactivity of Mao Luang Fruits (Molecules (Basel, Switzerland) · 2019Article
- The potential of antioxidant-rich Maoberry (Antidesma bunius) extract on fat metabolism in liver tissues of rats fed a high-fat diet.BMC complementary and alternative medicine · 2019Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
backgoundChronic fat-rich diets consumption is increased risk associated with cardiovascular diseases (CVD). Prevention or reduction the progression of cardiac tissue deterioration could benefit in CVD. This study aimed to examine the effects of maoberry (Antidesma bunius), a antioxidant-rich tropical fruit, supplementation on oxidative stress and inflammation in cardiac tissues of rats fed a high-fat diet (HFD).
methodsThe male rats orally received HFD with maoberry extract doses of 0.38, 0.76 or 1.52 g/kg or simvastatin (10 mg/kg) for 12 weeks. At the end of the experimental period, the rats were fasted, euthanized and harvested for the hearts.
resultsSignificantly reduced oxidative stress (malondialdehyde levels) and enhanced antioxidant capacity (ferric-reducing activities) in cardiac tissues of the rats were found. Maoberry extract remarkably ameliorated the expressions of genes involved with pro-inflammatory such as the tumor necrosis factor alpha (TNF-α), interleukin-6 (IL-6), vascular cell adhesion molecule-1 (VCAM-1), monocyte chemoattractant protein-1 (MCP-1) and endothelial nitric oxide synthase (eNOS).
conclusionsOur findings suggest that maoberry extract has remarkable effects on preventing progression of cardiac tissue deterioration at least through lowering oxidative stress and inflammation.
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