ArticleBMC infectious diseases2018
Is primary meningococcal arthritis in children more frequent than we expect? Two pediatric case reports revealed by molecular test.
Article in BMC infectious diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 14 citations in OpenAlex.
- Primary Septic Arthritis of the Hip Caused by Neisseria meningitidis Serogroup W135 in an Infant.Cureus · 2026Article
- Molecular Diagnosis in Culture-Negative Meningococcal Arthritis: A Case Report and Case-Based Literature Review.Mediterranean journal of rheumatology · 2025Article
- Two Cases of Rare Manifestations Due toMicroorganisms · 2025Article
- The Diverse Spectrum of Invasive Meningococcal Disease in Pediatric and Adolescent Patients: Narrative Review of Cases and Case Series.Infectious diseases and therapy · 2024Review
- Pathogens in Pediatric Septic Arthritis: A Multi-Center Study in Turkiye (PEDSART Study).Children (Basel, Switzerland) · 2024Article
- Review
- [Primary meningococcal arthritis].Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2021Article
- Child with serogroup W135 primary meningococcal septic arthritis.BMJ case reports · 2019Article
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPrimary meningococcal arthritis is a rare infectious disease that occurs in less than 3% of meningococcal infections and is characterized by arthritis without meningitis, fever, rash, or hemodynamic instability Barahona [Case Rep Orthop 4696014:2017 ]. There are no validated clinical criteria that can be used for the diagnosis. We present two pediatric cases of atypical presentation of meningococcal disease revealed by molecular tests. CASE PRESENTATION: The clinical presentation of the two children (6- and 9-years-old) was characterized by signs of arthritis. By Real Time Polymerase Chain Reaction (RT-PCR), we identified N. meningitidis serogroup Y in the joint fluid in both cases. After specific antimicrobial treatment, the clinical conditions of the two patients quickly improved during hospitalization.
conclusionsWe believe that the incidence of meningococcal arthritis could be underestimated in those settings where the use of RT-PCR is limited. Clearer data on the incidence of meningococcal disease would help to design specific treatments and the best possible national vaccine strategies [Fiji Sci Rep 23:39784, 2016, J Infect 67:385-90, 2013].
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