ArticleBrain and behavior2019
Resting-state connectivity within and across neural circuits in anorexia nervosa.
Article in Brain and behavior, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 32 citations in OpenAlex.
- Disrupted Salience Network and Its Deteriorated Interaction With the Central Executive Network in Anorexia Nervosa: A Multicenter Study.Biological psychiatry global open science · 2026Article
- From lobotomy to connectomics: a critical review of contemporary psychosurgery.Frontiers in psychiatry · 2026Review
- Psychedelics and Eating Disorders: Exploring the Therapeutic Potential for Anorexia Nervosa and Beyond.ACS pharmacology & translational science · 2025Review
- Food choice and neural reward systems in adolescents with anorexia nervosa and atypical anorexia nervosa.Journal of child psychology and psychiatry, and allied disciplines · 2025Article
- Neuroimaging studies of resting-state functional magnetic resonance imaging in eating disorders.BMC medical imaging · 2024Review
- Reduced dorsal fronto-striatal connectivity at rest in anorexia nervosa.Psychological medicine · 2024Article
- Nucleus accumbens D1- and D2-expressing neurons control the balance between feeding and activity-mediated energy expenditure.Nature communications · 2024Article
- Impaired maturation of resting-state connectivity in anorexia nervosa from adolescence to adulthood: differential mechanisms of consummatory vs. anticipatory responses through a symptom provocation paradigm.Frontiers in behavioral neuroscience · 2024Article
- Altered functional connectivity between cortical networks associated with inhibitory control in trauma-exposed females.Psychiatry research. Neuroimaging · 2023Article
- Large-Scale Exploration of Whole-Brain Structural Connectivity in Anorexia Nervosa: Alterations in the Connectivity of Frontal and Subcortical Networks.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2023Article
- Disrupted longitudinal restoration of brain connectivity during weight normalization in severe anorexia nervosa.Translational psychiatry · 2023Article
- Longitudinal study in adolescent anorexia nervosa: evaluation of cortico-striatal and default mode network resting-state brain circuits.European child & adolescent psychiatry · 2023Article
- Neural correlates of a mindfulness-based intervention in anorexia nervosa.BJPsych open · 2023Article
- Article
- Potential biomarker of brain response to opioid antagonism in adolescents with eating disorders: a pilot study.Frontiers in psychiatry · 2023Article
- Associations of observed preschool performance monitoring with brain functional connectivity in adolescence.Cortex; a journal devoted to the study of the nervous system and behavior · 2021Article
- Changes in brain and behavior during food-based decision-making following treatment of anorexia nervosa.Journal of eating disorders · 2021Article
- Neuroimaging Findings in Adolescents and Young Adults with Anorexia Nervosa: A Systematic Review.Children (Basel, Switzerland) · 2021Review
- Peripheral serotonin transporter DNA methylation is linked to increased salience network connectivity in females with anorexia nervosaJournal of psychiatry & neuroscience : JPN · 2020Article
- Strengthened Default Mode Network Activation During Delay Discounting in Adolescents with Anorexia Nervosa After Partial Weight Restoration: A Longitudinal fMRI Study.Journal of clinical medicine · 2020Article
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
introductionObsessional thoughts and ritualized eating behaviors are characteristic of Anorexia Nervosa (AN), leading to the common suggestion that the illness shares neurobiology with obsessive-compulsive disorder (OCD). Resting-state functional connectivity MRI (rs-fcMRI) is a measure of functional neural architecture. This longitudinal study examined functional connectivity in AN within the limbic cortico-striato-thalamo-cortical (CSTC) loop, as well as in the salience network, the default mode network, and the executive control network (components of the triple network model of psychopathology).
methodsResting-state functional connectivity MRI scans were collected in unmedicated female inpatients with AN (n = 25) and healthy controls (HC; n = 24). Individuals with AN were scanned before and after weight restoration and followed for one month after hospital discharge. HC were scanned twice over the same timeframe.
resultsUsing a seed-based correlation approach, individuals with AN had increased connectivity within the limbic CSTC loop when underweight, only. There was no significant association between limbic CSTC connectivity and obsessive-compulsive symptoms or prognosis. Exploratory analyses of functional network connectivity within the triple network model showed reduced connectivity between the salience network and left executive control network among AN relative to HC. These abnormalities persisted following weight restoration.
conclusionsThe CSTC findings suggest that the neural underpinnings of obsessive-compulsive symptoms may differ from those of OCD. The inter-network abnormalities warrant examination in relation to illness-specific behaviors, namely abnormal eating behavior. This longitudinal study highlights the complexity of the neural underpinnings of AN.
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