Evidence map›Paper›PMID 30590737›Full record

ArticlePain medicine (Malden, Mass.)2019

Mitigating the Effect of Pain Severity on Activity and Disability in Patients with Chronic Pain: The Crucial Context of Acceptance.

Kathryn E Kanzler, Jacqueline A Pugh, Donald D McGeary, Willie J Hale, Charles W Mathias, Lisa S Kilpela, Tara E Karns-Wright, Patricia J Robinson, Sara A Dixon, Craig J Bryan and 2 more

Abstract read
In one paragraph

Article in Pain medicine (Malden, Mass.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. The mediating role of posttraumatic stress disorder symptoms in pain cognitions among Veterans with chronic pain.Military psychology : the official journal of the Division of Military Psychology, American Psychological Association · 2025
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  12. The Role of Pain Inflexibility and Acceptance among Headache and Temporomandibular Disorders Patients.International journal of environmental research and public health · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Kathryn E KanzlerDepartment of Psychiatry, University of Texas Health Science Center San Antonio, San Antonio, Texas.
Jacqueline A PughSouth Texas Veterans Health Care System.
Donald D McGearyDepartment of Psychiatry, University of Texas Health Science Center San Antonio, San Antonio, Texas.
Willie J HaleDepartment of Psychology, The University of Texas at San Antonio, San Antonio, Texas, USA.
Charles W MathiasDepartment of Psychiatry, University of Texas Health Science Center San Antonio, San Antonio, Texas.
Lisa S KilpelaDepartment of Psychiatry, University of Texas Health Science Center San Antonio, San Antonio, Texas.
Tara E Karns-WrightDepartment of Psychiatry, University of Texas Health Science Center San Antonio, San Antonio, Texas.
Patricia J RobinsonMountainview Consulting Group.
Sara A Dixon81 DS/SGD Orofacial Pain, Keesler Air Force Base.
Craig J BryanNational Center for Veterans Studies and Department of Psychology, University of Utah, Salt Lake City, Utah, USA.
John C MoringSouth Texas Veterans Health Care System.
Lance M McCrackenPsychology Department, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.

Funding

San Antonio OAIC - Research Education Component (REC)P30AG044271 · NIA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI Blake B Rasmussen · 2015 to 2026
$14.1M
Institutional Career Development Core (KL2)KL2TR002646 · NCATS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI TSEVAT, JOEL · 2018 to 2022
$3.4M
Institute for Integration of Medicine & Science: A Partnership to Improve HealthKL2TR001118 · NCATS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI CLARK, ROBERT A, DOUGHERTY, DONALD M · 2013 to 2017
$3.4M
NCATS NIH HHS KL2 TR001118NCATS NIH HHS KL2 TR002646NIA NIH HHS P30 AG044271
6 · The paper itself

Abstract

objectiveThe purpose of this study was to examine the effect of pain severity on activity levels and physical disability in the context of high pain acceptance. We hypothesized that pain acceptance moderates the effect of pain severity on general activity and physical disability, such that at higher levels of acceptance, the deleterious effect of pain is mitigated.

methodsTwo hundred seven patients with chronic pain were recruited from three clinics in a large southwestern military treatment facility. Participants completed an anonymous self-report battery of standardized measures, including the Chronic Pain Acceptance Questionnaire, modified Oswestry Disability Index, and Pain Severity and General Activity subscales of the West Haven-Yale Multidimensional Pain Inventory.

resultsChronic pain acceptance was found to significantly moderate relations between pain severity and general activity (b  =  0.0061, t(198) = 2.75, P = 0.007, 95% confidence interval [CI] = 0.002 to 0.011) and pain severity and disability (b  =  0.036, t(193) = -2.564, P = 0.011, 95% CI = -0.063 to -0.008). In the context of higher acceptance, the negative effect of pain on activity and disability appeared reduced. Conversely, in the context of low acceptance, the effect of pain on disability appeared accentuated at all levels of pain severity.

conclusionsHigher acceptance mitigated both activity level and disability in a military-affiliated clinical sample of patients with chronic pain. Results further establish the role of acceptance in relation to functioning in a unique sample of people with chronic pain. These findings have implications for understanding and enhancing functioning in chronic pain populations.

Indexed as

Activities of Daily LivingAttitude to HealthChronic PainFamilyFemaleHumansMaleMilitary PersonnelPain ManagementPain MeasurementSeverity of Illness IndexVeteransAcceptanceActivityChronic PainDisabilityFunctioning

Identifiers

PMID30590737
PMCPMC6686120

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.