ArticleThe Journal of nutrition2019
Postprandial Duration Influences the Association of Insulin-Related Dietary Indexes and Plasma C-peptide Concentrations in Adult Men and Women.
Article in The Journal of nutrition, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 20 citations in OpenAlex.
- Harnessing Metabolic Insights: A Framework for Dietary Patterns in Chronic Disease Prevention and Management.Advances in nutrition (Bethesda, Md.) · 2026Review
- Association of serum magnesium level with small fiber neuropathy in patients with type 2 diabetes.Frontiers in medicine · 2025Article
- Insulinemic potential of diet and the risk of type 2 diabetes: a meta-analysis and systematic review.Diabetology & metabolic syndrome · 2024Review
- Insulinaemic potential of diet and lifestyle and risk of type 2 diabetes in the Iranian adults: result from Yazd health study.BMC endocrine disorders · 2023Article
- Metabolically defined body size and body shape phenotypes and risk of postmenopausal breast cancer in the European Prospective Investigation into Cancer and Nutrition.Cancer medicine · 2023Article
- Unrestrained eating behavior and risk of digestive system cancers: a prospective cohort study.The American journal of clinical nutrition · 2021Article
- Associations of Dairy Intake with Circulating Biomarkers of Inflammation, Insulin Response, and Dyslipidemia among Postmenopausal Women.Journal of the Academy of Nutrition and Dietetics · 2021Article
- Association of the insulinemic potential of diet and lifestyle with risk of diabetes incident in Tehranian adults: a population based cohort study.Nutrition journal · 2021Article
- Incident Type 2 Diabetes Duration and Cancer Risk: A Prospective Study in Two US Cohorts.Journal of the National Cancer Institute · 2021Article
- Association of Inflammatory and Insulinemic Potential of Diet and Lifestyle with Risk of Hepatocellular Carcinoma.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2021Article
- Dietary Inflammatory and Insulinemic Potential and Risk of Type 2 Diabetes: Results From Three Prospective U.S. Cohort Studies.Diabetes care · 2020Article
- Post-diagnosis dietary insulinemic potential and survival outcomes among colorectal cancer patients.BMC cancer · 2020Article
- Identifying Metabolomic Profiles of Insulinemic Dietary Patterns.Metabolites · 2019Article
- Long-Term Change in both Dietary Insulinemic and Inflammatory Potential Is Associated with Weight Gain in Adult Women and Men.The Journal of nutrition · 2019Article
- Association of the Insulinemic Potential of Diet and Lifestyle With Risk of Digestive System Cancers in Men and Women.JNCI cancer spectrum · 2018Article
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Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundThe dietary insulin index (II) directly quantifies dietary effects on postprandial insulin secretion, whereas the empirical dietary index for hyperinsulinemia (EDIH), based on fasting C-peptide concentrations, is primarily reflective of insulin resistance. How these scores are related to nonfasting C-peptide in cohort studies has not been examined.
objectiveWe investigated the extent to which EDIH and II scores predict plasma C-peptide concentrations, in cross-sectional analyses by postprandial duration at blood collection from 1 to ≥15 h.
methodsBoth EDIH and II scores were calculated from food-frequency questionnaire data reported by 3964 men in the Health Professionals Follow-up Study (1993-1995) and 6215 women in the Nurses' Health Study (1989-1990) who were not diabetic. We constructed 12 multivariable-adjusted linear regression models separately in men and women, by postprandial duration, to calculate relative differences and absolute values of plasma C-peptide concentrations in dietary index quintiles.
resultsIn both men and women, C-peptide concentrations were elevated 1-2 h after eating and declined with increasing postprandial duration. In men, percent differences in C-peptide concentration in the highest compared with lowest dietary index quintile were: EDIH: 0-1 h: 50%; 2 h: 22%; 14 h: 14%; ≥15 h: 30% (all P-trend< 0.05). II: 0-1 h: 19% (P-trend = 0.09); 2 h: 3% (P-trend = 0.09); 14 h: -6% (P-trend = 0.17); ≥15 h: -15% (P-trend = 0.02). Corresponding results among women were: EDIH: 0-1 h: 29% (P-trend = 0.002); 2 h: 33% (P-trend = 0.009); 14 h: 44% (P-trend < 0.0001); ≥15 h: 40% (P-trend < 0.0001). II: 0-1 h: -12% (P-trend = 0.09); 2 h: 17% (P-trend = 0.09); 14 h: -14% (P-trend = 0.009); ≥15 h: -3% (P-trend = 0.37).
conclusionThe EDIH was superior to the II in predicting both fasting and nonfasting C-peptide concentrations, suggesting that the EDIH may be better in assessing dietary effects of hyperinsulinemia on disease risk in adult men and women.
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