SynthesisClinical infectious diseases : an official publication of the Infectious Diseases Society of America2019
Drug Use and Postoperative Mortality Following Valve Surgery for Infective Endocarditis: A Systematic Review and Meta-analysis.
Synthesis in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.
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Who cites it
28 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Sarcopenia as a prognostic indicator in colorectal cancer: an updated meta-analysis.Frontiers in oncology · 2023Pooled it
- Long term surgical outcomes for infective endocarditis in people who inject drugs: a systematic review and meta-analysis.BMC infectious diseases · 2019Pooled it
- Infective endocarditis: it takes a team.European heart journal · 2025Review
- Surgical Intervention for Isolated Tricuspid Valve Endocarditis-Refining Patients' Selection.Avicenna journal of medicine · 2025Article
- Substance Use and Outcomes of Left-Sided Valve Replacement in Patients With Infective Endocarditis.Annals of thoracic surgery short reports · 2024Article
- Percutaneous Mechanical Aspiration for Infective Endocarditis: Proceedings From an Inaugural Multidisciplinary Summit and Comprehensive Review.Journal of the Society for Cardiovascular Angiography & Interventions · 2024Review
- Article
- Article
- Strategies to Improve Patient-Centered Care for Drug Use-Associated Infective Endocarditis: JACC Focus Seminar 2/4.Journal of the American College of Cardiology · 2024Review
- Epidemiology of acute infections in people who inject drugs in Australia.Drug and alcohol review · 2024Review
- Five-Year Cardiovascular Outcomes after Infective Endocarditis in Patients with versus without Drug Use History.Journal of personalized medicine · 2022Article
- Article
- Review of management priorities for invasive infections in people who inject drugs: highlighting the need for patient-centred multidisciplinary care.The Medical journal of Australia · 2022Review
- Expanding the Team: Optimizing the Multidisciplinary Management of Drug Use-Associated Infective Endocarditis.Journal of general internal medicine · 2022Article
- Article
- Article
- The Evolving Burden of Drug Use Associated Infective Endocarditis in the United States.The Annals of thoracic surgery · 2020Article
- Surgical treatment of infective endocarditis: Results in 831 patients from a single center.Journal of cardiac surgery · 2020Article
- Applying the Infectious Diseases Literature to People who Inject Drugs.Infectious disease clinics of North America · 2020Review
- Infective Endocarditis in Persons Who Use Drugs: Epidemiology, Current Management, and Emerging Treatments.Infectious disease clinics of North America · 2020Review
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
backgroundInfective endocarditis (IE) often requires surgical intervention. An increasingly common cause of IE is injection drug use (IDU-IE). There is conflicting evidence on whether postoperative mortality differs between people with IDU-IE and people with IE from etiologies other than injection drug use (non-IDU-IE). In this manuscript, we compare short-term postoperative mortality in IDU-IE vs non-IDU-IE through systematic review and meta-analysis.
methodsThe review was conducted according to the Cochrane Handbook for Systematic Reviews of Interventions and the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Publication databases were queried for key terms included in articles up to September 2017. Randomized controlled trials, prospective cohorts, or retrospective cohorts that reported on 30-day mortality or in-hospital/operative mortality following valve surgery and that compared outcomes between IDU-IE and non-IDU-IE were included.
resultsThirteen studies with 1593 patients (n = 341 [21.4%] IDU-IE) were included in the meta-analysis. IDU-IE patients more frequently had tricuspid valve infection, Staphylococcus infection, and heart failure before surgery. Meta-analysis revealed no statistically significant difference in 30-day postsurgical mortality or in-hospital mortality between the 2 groups.
conclusionsDespite differing preoperative clinical characteristics, early postoperative mortality does not differ between IDU-IE and non-IDU-IE patients who undergo valve surgery. Future research on long-term outcomes following valve replacement is needed to identify opportunities for improved healthcare delivery with IDU-IE.
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