ArticleCell reports2018
REV-ERBα Regulates T
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Article in Cell reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 83 papers.
0numbers the graph read from it
0cells of the map it votes in
83citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
83 citing papers in PubMed, 109 citations in OpenAlex.
- Time matters: circadian genetics and the molecular logic of human health and disease.Nature reviews. Genetics · 2026Review
- REV-ERB-Mediated Regulation of Neural Functional Mechanisms by Phytochemicals in the Circadian System.Nutrients · 2026Review
- A single-cell atlas of porcine hematopoietic development.Nature communications · 2026Article
- Circadian Disruption Exacerbates Innate Immune Responses by Modulating the Bistability of Pro-Inflammatory Signaling: A Dynamical Modeling Study.Biomedicines · 2026Article
- Chemical biology approaches to study and target circadian clocks and their components.FEBS letters · 2026Review
- REV-ERB regulates RORγt+ regulatory T cell specification and function through the Bhlhe40-c-Maf axis.The Journal of experimental medicine · 2026Article
- The Circadian Rhythm Regulates the Hepato-ovarian Axis Linking Polycystic Ovary Syndrome and Non-alcoholic Fatty Liver Disease.Biochemical genetics · 2026Article
- Negative regulation of TbioRxiv : the preprint server for biology · 2026Article
- CCL20-CCR6 signaling alters the metabolic reprogramming to promote the pathogenic Th17 cell differentiation.iScience · 2026Article
- Modulation of TH17 cell activity by REV-ERB agonists: path toward novel treatments for canine meningoencephalitis of unknown origin.npj veterinary sciences · 2026Review
- Circadian clock regulation in lung health and disease: molecular mechanisms and therapeutic opportunities.EXCLI journal · 2026Review
- Effects and Mechanisms of Wrist-Ankle Acupuncture on Inflammatory Pain in the Rat Gastrocnemius Muscle.Journal of pain research · 2026Article
- NR1D1-Mediated Suppression of JAK1/STAT3 Signaling Contributes to the Therapeutic Effects of Triptolide in Rheumatoid Arthritis.Mediators of inflammation · 2026Article
- Limited effects of the REV-ERB agonist SR9009 after mouse spinal cord contusion: Reduced acute pathology with unaffected functional recovery and chronic white matter loss.Neuroscience letters · 2026Article
- Circadian Clock: A Regulator of Immunity in Autoimmune Diseases.Immunity, inflammation and disease · 2025Review
- Circadian circuits control plasticity of group 3 innate lymphoid cells by sustaining epigenetic configuration of RORγt.Nature immunology · 2025Article
- Article
- Circadian Clock Disruption and Non-type 2 Asthma: A Hypothesis-Driven Perspective on Immune, Epithelial, and Steroid Response.Clinical reviews in allergy & immunology · 2025Review
- Biological Clock Perspective in Rheumatoid Arthritis.Inflammation · 2025Review
- Peripheral Transcriptome of Severe Sarcoidosis Involves Dysregulation of Multiple Immunologic Systems.American journal of respiratory cell and molecular biology · 2025Article
23 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors at 1 institution in 1 country.
Mohammed AmirDepartment of Immunology and Microbiology, The Scripps Research Institute, Jupiter, Florida 33458, USA.
Sweena ChaudhariDepartment of Immunology and Microbiology, The Scripps Research Institute, Jupiter, Florida 33458, USA.
Ran WangDepartment of Immunology and Microbiology, The Scripps Research Institute, Jupiter, Florida 33458, USA.
Sean CampbellDepartment of Immunology and Microbiology, The Scripps Research Institute, Jupiter, Florida 33458, USA.
Sarah A MosureDepartment of Immunology and Microbiology, The Scripps Research Institute, Jupiter, Florida 33458, USA; Scripps Research, Skaggs Graduate School of Chemical and Biological Sciences, The Scripps Research Institute, La Jolla, California 92037, USA; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, Jupiter, Florida 33458, USA.
Laura B ChoppDepartment of Immunology and Microbiology, The Scripps Research Institute, Jupiter, Florida 33458, USA.
Qun LuDepartment of Immunology and Microbiology, The Scripps Research Institute, Jupiter, Florida 33458, USA; Department of Molecular Medicine, The Scripps Research Institute, Jupiter, Florida 33458, USA.
Jinsai ShangDepartment of Integrative Structural and Computational Biology, The Scripps Research Institute, Jupiter, Florida 33458, USA.
Oliver B PelletierDepartment of Immunology and Microbiology, The Scripps Research Institute, Jupiter, Florida 33458, USA.
Yuanjun HeDepartment of Molecular Medicine, The Scripps Research Institute, Jupiter, Florida 33458, USA.
Christelle DoebelinDepartment of Molecular Medicine, The Scripps Research Institute, Jupiter, Florida 33458, USA.
Michael D CameronDepartment of Molecular Medicine, The Scripps Research Institute, Jupiter, Florida 33458, USA.
Douglas J KojetinDepartment of Integrative Structural and Computational Biology, The Scripps Research Institute, Jupiter, Florida 33458, USA.
Theodore M KameneckaDepartment of Molecular Medicine, The Scripps Research Institute, Jupiter, Florida 33458, USA.
Laura A SoltDepartment of Immunology and Microbiology, The Scripps Research Institute, Jupiter, Florida 33458, USA; Department of Molecular Medicine, The Scripps Research Institute, Jupiter, Florida 33458, USA. Electronic address: lsolt@scripps.edu.
Scripps Research Institute · US
Funding
Regulation of TH17 Cell Development and Function by the REV-ERBsR01AI116885 · NIAID · SCRIPPS FLORIDA · PI SOLT, LAURA A · 2016 to 2020
$2.1MStructural mechanism and function of endogenous ligands targeting orphan NR4A receptorsR01GM114420 · NIGMS · SCRIPPS FLORIDA · PI KOJETIN, DOUGLAS · 2015 to 2018
$1.5MNIAID NIH HHS R01 AI116885NIGMS NIH HHS R01 GM114420
Abstract
RORγt is well recognized as the lineage-defining transcription factor for T helper 17 (T
Indexed as
AutoimmunityAnimalsColitisDisease ProgressionEncephalomyelitis, Autoimmune, ExperimentalFemaleHEK293 CellsHumansInflammationMaleMice, Inbred C57BLNuclear Receptor Subfamily 1, Group D, Member 1Nuclear Receptor Subfamily 1, Group F, Member 3Th17 CellsUp-RegulationNuclear Receptor Subfamily 1, Group D, Member 1Nuclear Receptor Subfamily 1, Group F, Member 3autoimmunitycircadianIL-17AREV-ERBRORγtSR9009T cellsTh17
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.