Evidence map›Paper›PMID 30589665›Full record

ArticlePsychosomatic medicine2019

Associations Between Cannabis Use and Cardiometabolic Risk Factors: A Longitudinal Study of Men.

Madeline H Meier, Dustin Pardini, Jordan Beardslee, Karen A Matthews

Abstract read
In one paragraph

Article in Psychosomatic medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. A Review of the Effects of Adolescent Cannabis Use on Physical Health.The Psychiatric clinics of North America · 2023
    Review
  7. Article
  8. A Review of the Effects of Adolescent Cannabis Use on Physical Health.Child and adolescent psychiatric clinics of North America · 2023
    Review
  9. Article
  10. Article
  11. Fetal Exposure to Cannabis and Childhood Metabolic Outcomes: The Healthy Start Study.The Journal of clinical endocrinology and metabolism · 2022
    Article
  12. Article
  13. The effects of cannabis and cannabinoids on the endocrine system.Reviews in endocrine & metabolic disorders · 2022
    Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. Vaporized Cannabis Extracts Have Reinforcing Properties and Support Conditioned Drug-Seeking Behavior in Rats.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Madeline H MeierFrom the Departments of Psychology (Meier) and Criminology and Criminal Justice (Pardini), Arizona State University, Tempe, Arizona; and Department of Psychiatry (Beardslee, Matthews), University of Pittsburgh, Pennsylvania.
Dustin Pardini
Jordan Beardslee
Karen A Matthews

Funding

TRACING DIVERGING LIVES AND CONVERGING PROBLEMSR01MH050778 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI LOEBER, ROLF · 1993 to 2005
$2.2M
Early Life Adversity, Sleep, and Cardiovascular Risk in Black and White MenR01HL111802 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MATTHEWS, KAREN · 2012 to 2014
$2.1M
NHLBI NIH HHS R01 HL111802NIMH NIH HHS R01 MH050778
6 · The paper itself

Abstract

objectiveThis study tested longitudinal associations between cannabis use and cardiometabolic risk factors that underlie the development of cardiovascular diseases.

methodsParticipants were men from the youngest cohort of the Pittsburgh Youth Study who were followed prospectively from approximately age 7 to 32 years (N = 253). Frequency of cannabis use was assessed yearly from approximately ages 12 to 20 years and again at approximately ages 26, 29, and 32 years. The following cardiometabolic risk factors were assessed during a laboratory visit at approximately age 32 years: body mass index (BMI), waist-hip ratio, high- and low-density lipoprotein cholesterol, triglycerides, fasting glucose, insulin resistance, blood pressure, interleukin 6, and C-reactive protein.

resultsGreater cannabis exposure was associated with relatively lower BMI (β = -0.31, p < .001), smaller waist-hip ratio (β = -0.23, p = .002), better high- (β = 0.14, p = .036) and low-density lipoprotein cholesterol (β = -0.15, p = .026), lower triglycerides (β = -0.17, p = .009), lower fasting glucose (β = -0.15, p < .001) and insulin resistance (β = -0.21, p = .003), lower systolic (β = -0.22, p < .001) and diastolic blood pressure (β = -0.15, p = .028), and fewer metabolic syndrome criteria (β = -0.27, p < .001). With exception of BMI, cannabis users' mean levels on cardiometabolic risk factors were generally below clinical cutoffs for high risk. Most associations between cannabis use and cardiometabolic risk factors remained after adjusting for tobacco use, childhood socioeconomic status, and childhood health. However, after adjusting for adult BMI, these associations were no longer apparent, and mediation tests suggested that cannabis users' relatively lower BMI might explain their lower levels of risk on other cardiometabolic risk factors.

conclusionsCannabis use is associated with lower BMI, and lower BMI is related to lower levels of risk on other cardiometabolic risk factors.

Indexed as

Body Mass IndexWaist-Hip RatioAdolescentAdultBlood GlucoseBlood PressureCardiovascular DiseasesChildCholesterolHumansInsulin ResistanceLongitudinal StudiesMaleMarijuana UseMetabolic SyndromeRiskBlood GlucoseCholesterol

Identifiers

PMID30589665
PMCPMC6443484

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.