ArticleeLife2018
Transcriptomic analysis reveals reduced transcriptional activity in the malaria parasite
Open access · goldAbstract read
In one paragraph
Article in eLife, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
5.1field-weighted citation impact, top 5% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 68 citations in OpenAlex.
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- Transfection Models to InvestigatePathogens (Basel, Switzerland) · 2023Review
- Transcriptional profiling of hepatocytes infected with the replicative form of the malaria parasite Plasmodium cynomolgi.Malaria journal · 2022Article
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- Temperate climate malaria in nineteenth century Denmark.BMC infectious diseases · 2022Article
- In vitro maturation of Toxoplasma gondii bradyzoites in human myotubes and their metabolomic characterization.Nature communications · 2022Article
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- Plasmodium vivax Liver and Blood Stages Recruit the Druggable Host Membrane Channel Aquaporin-3.Cell chemical biology · 2020Article
- Dual-Luciferase-Based Fast and Sensitive Detection of Malaria Hypnozoites for the Discovery of Antirelapse Compounds.Analytical chemistry · 2020Article
- Tafenoquine: A Step toward Malaria Elimination.Biochemistry · 2020Article
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- Modeling Relapsing Malaria: Emerging Technologies to Study Parasite-Host Interactions in the Liver.Frontiers in cellular and infection microbiology · 2020Review
- Parasite-Host Interaction and Pathophysiology Studies of the Human Relapsing MalariasFrontiers in cellular and infection microbiology · 2020Review
- Preparing for Transmission: Gene Regulation inFrontiers in cellular and infection microbiology · 2020Review
- Protozoan persister-like cells and drug treatment failure.Nature reviews. Microbiology · 2019Review
- Functional genomics of simian malaria parasites and host-parasite interactions.Briefings in functional genomics · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
24 authors at 4 institutions in 4 countries.
Nicole L Bertschi *Novartis Institutes for BioMedical Research, Novartis Pharma AG, Basel, Europe.
Annemarie Voorberg-van der Wel *Department of Parasitology, Biomedical Primate Research Centre, Rijswijk, The Netherlands.ORCID http://orcid.org/0000-0001-9403-0515
Anne-Marie ZeemanDepartment of Parasitology, Biomedical Primate Research Centre, Rijswijk, The Netherlands.
Sven SchuiererNovartis Institutes for BioMedical Research, Novartis Pharma AG, Basel, Europe.
Florian NigschNovartis Institutes for BioMedical Research, Novartis Pharma AG, Basel, Europe.
Walter CarboneNovartis Institutes for BioMedical Research, Novartis Pharma AG, Basel, Europe.ORCID https://orcid.org/0000-0001-6150-8295
Judith KnehrNovartis Institutes for BioMedical Research, Novartis Pharma AG, Basel, Europe.
Devendra K GuptaNovartis Institute for Tropical Diseases, Novartis Pharma AG, Emeryville, United States.
Sam O HofmanDepartment of Parasitology, Biomedical Primate Research Centre, Rijswijk, The Netherlands.
Nicole van der WerffDepartment of Parasitology, Biomedical Primate Research Centre, Rijswijk, The Netherlands.
Ivonne NieuwenhuisDepartment of Parasitology, Biomedical Primate Research Centre, Rijswijk, The Netherlands.
Els KloosterDepartment of Parasitology, Biomedical Primate Research Centre, Rijswijk, The Netherlands.
Bart W FaberDepartment of Parasitology, Biomedical Primate Research Centre, Rijswijk, The Netherlands.
Erika L FlanneryNovartis Institute for Tropical Diseases, Novartis Pharma AG, Emeryville, United States.ORCID https://orcid.org/0000-0003-0665-7954
Sebastian A MikolajczakNovartis Institute for Tropical Diseases, Novartis Pharma AG, Emeryville, United States.
Vorada ChuenchobNovartis Institute for Tropical Diseases, Novartis Pharma AG, Emeryville, United States.
Binesh ShresthaNovartis Institutes for BioMedical Research, Novartis Pharma AG, Basel, Europe.
Martin BeibelNovartis Institutes for BioMedical Research, Novartis Pharma AG, Basel, Europe.
Tewis BouwmeesterNovartis Institutes for BioMedical Research, Novartis Pharma AG, Basel, Europe.
Niwat KangwanrangsanDepartment of Pathobiology, Faculty of Science, Mahidol University, Bangkok, Thailand.
Jetsumon SattabongkotMahidol Vivax Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.ORCID https://orcid.org/0000-0002-3938-4588
Thierry T DiaganaNovartis Institute for Tropical Diseases, Novartis Pharma AG, Emeryville, United States.ORCID https://orcid.org/0000-0002-8520-5683
Clemens Hm KockenDepartment of Parasitology, Biomedical Primate Research Centre, Rijswijk, The Netherlands.
Guglielmo RomaNovartis Institutes for BioMedical Research, Novartis Pharma AG, Basel, Europe.ORCID https://orcid.org/0000-0002-8020-4219
Novartis (Switzerland) · CHBiomedical Primate Research Centre · NLNovartis (United States) · USMahidol University · TH
Funding
Wellcome Trust
Abstract
Relapses of
Indexed as
Gene Expression ProfilingAnimalsLiverPlasmodium cynomolgiPrimatesTime Factorshypnozoitesinfectious diseaseliver stagesmalariamaturationmicrobiologyplasmodiumtranscriptomics
Identifiers
What OpenQuestion holds
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LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.