Evidence map›Paper›PMID 30588900›Full record

ArticlePublic health nutrition2019

Effects of a lifestyle intervention on markers of cardiometabolic risk and oxidized lipoproteins among obese adolescents with prediabetes.

Ana Rentería-Mexía, Sonia Vega-López, Micah L Olson, Pamela D Swan, Chong D Lee, Allison N Williams, Gabriel Q Shaibi

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in Public health nutrition, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02039141 (Community-Based Diabetes Prevention Program for Obese Latino Youth), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02039141 nacompletednot on this map

Community-Based Diabetes Prevention Program for Obese Latino Youth: Every Little Step Counts

TypeinterventionalSponsorArizona State UniversityRan2012 to 2016Enrolled160ConditionsObesity, Insulin Resistance, DiabetesArmsEvery Little Step Counts Intervention
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 8 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Ana Rentería-MexíaDepartamento de Biotecnología y Ciencias Alimentarias Instituto Tecnológico de Sonora, Obregón, Sonora, México.
Sonia Vega-LópezSchool of Nutrition and Health Promotion, Arizona State University, Phoenix, AZ, USA.ORCID https://orcid.org/0000-0001-8089-0725
Micah L OlsonDivision of Endocrinology and Diabetes, Phoenix Children's Hospital, Phoenix, AZ, USA.
Pamela D SwanSchool of Nutrition and Health Promotion, Arizona State University, Phoenix, AZ, USA.
Chong D LeeSchool of Nutrition and Health Promotion, Arizona State University, Phoenix, AZ, USA.
Allison N WilliamsCenter for Health Promotion and Disease Prevention, College of Nursing and Health Innovation, Arizona State University, 500 N. 3rd Street, Phoenix, AZ 85004, USA.
Gabriel Q ShaibiSchool of Nutrition and Health Promotion, Arizona State University, Phoenix, AZ, USA.
Arizona State University · USPhoenix Children's Hospital · USSonora Institute of Technology · MX

Funding

Urban American Indian Youth Substance Use: Ecodevelopmental Influences P20MD002316 · NIMHD · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI MARSIGLIA, FLAVIO FRANCISCO · 2007 to 2016
$13.3M
Preventing Diabetes in Latino YouthR01DK107579 · NIDDK · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI SHAIBI, GABRIEL QUANTUM · 2016 to 2025
$6.9M
NIDDK NIH HHS R01 DK107579NIMHD NIH HHS P20 MD002316
6 · The paper itself

Abstract

objectiveObesity and hyperglycaemia contribute to the atherosclerotic process in part through oxidative modifications to lipoprotein particles. The present study aimed to evaluate the effects of a lifestyle intervention on markers of oxidized lipoproteins in obese Latino adolescents with prediabetes.

designPre-post design.

settingParticipants were enrolled into a 12-week lifestyle intervention. Measurements pre- and post-intervention included anthropometrics and body composition, lipid panel, oxidized LDL (oxLDL), oxidized HDL (oxHDL), intake of fresh fruits and vegetables, and cardiorespiratory fitness.

participantsThirty-five obese Latino adolescents (seventeen females, eighteen males; mean age 15·5 (sd 1·0) years; mean BMI percentile 98·5 (sd 1·2)) with prediabetes.

resultsIntervention participation resulted in significant reductions in weight (-1·2 %, P = 0·042), BMI and BMI percentile (-2·0 and -0·4 %, respectively, P < 0·001), body fat (-7·0 %, P = 0·025), TAG (-11·8 %, P = 0·032), total cholesterol (-5·0 %, P = 0·002), VLDL-cholesterol (-12·5 %, P = 0·029), and non-HDL-cholesterol (-6·7 %, P = 0·007). Additionally, fitness (6·4 %, P < 0·001) and intake of fruits and vegetables (42·4 %, P = 0·025) increased significantly. OxLDL decreased significantly after the intervention (51·0 (sd 14·0) v. 48·7 (sd 12·8) U/l, P = 0·022), while oxHDL trended towards a significant increase (395·2 (sd 94·6) v. 416·1 (sd 98·4) ng/ml, P = 0·056).

conclusionsThese data support the utility of lifestyle intervention to improve the atherogenic phenotype of Latino adolescents who are at high risk for developing premature CVD and type 2 diabetes.

Indexed as

Obese Latino adolescentsOxidized HDLOxidized LDLOxidized lipoproteinsPrediabetes

Identifiers

PMID30588900
PMCPMC6597339
OpenAlexW2907378797

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.