ArticleThe Journal of organic chemistry2019
Copper-Catalyzed Modular Amino Oxygenation of Alkenes: Access to Diverse 1,2-Amino Oxygen-Containing Skeletons.
Article in The Journal of organic chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Copper-Catalyzed Asymmetric Amino Lactonization of Alkenes: Direct Access to Enantioenriched 1,2-Alkylamino Alcohol Derivatives.Journal of the American Chemical Society · 2026Article
- Three-component synthesis of β-thio tertiary alkylamines from simple alkenes via SScience advances · 2026Article
- Copper-Catalyzed Allylic Amination of Alkenes UsingACS catalysis · 2025Article
- Copper-Catalyzed 1,4-Aminohydroxylation and Aminothiolation of 1,3-Dienes by Carbonyl-Assisted Migration.Chem catalysis · 2024Article
- Direct synthesis of branched amines enabled by dual-catalyzed allylic C─H amination of alkenes with amines.Science advances · 2024Article
- Copper-catalyzed generation of nitrogen-centered radicals and reactions thereof.ARKIVOC : free online journal of organic chemistry · 2024Article
- Development of New Reactions Driven by N-O Bond Cleavage: fromSynlett : accounts and rapid communications in synthetic organic chemistry · 2023Article
- Copper-Catalyzed Three-Component Aminofluorination of Alkenes and 1,3-Dienes: Direct Entry to Diverse β-Fluoroalkylamines.Journal of the American Chemical Society · 2022Article
- Pd-Catalyzed Alkene Diamination Reactions withThe Journal of organic chemistry · 2021Article
- Copper-Catalyzed Aminoheteroarylation of Unactivated Alkenes through Distal Heteroaryl Migration.ACS catalysis · 2021Article
- Chiral Hypervalent Iodine Catalysis Enables an Unusual Regiodivergent Intermolecular Olefin Aminooxygenation.JACS Au · 2021Article
- Halonium Catalysis: An Underutilized and Underexplored Catalytic Concept in Olefin Functionalizations.Synlett : accounts and rapid communications in synthetic organic chemistry · 2021Article
- Copper-Catalyzed Decarboxylative Functionalization of ConjugatedACS catalysis · 2020Article
- Copper-Catalyzed 1,2-Aminocyanation of Unactivated Alkenes via Cyano Migration.Organic letters · 2020Article
- AlkeneOrganic letters · 2020Article
- Iron-Mediated Electrophilic Amination of Organozinc Halides using Organic Azides.Angewandte Chemie (International ed. in English) · 2020Article
- Copper-Catalyzed 1,2-Amino Oxygenation of 1,3-Dienes: A Chemo-, Regio-, and Site-Selective Three-Component Reaction withACS catalysis · 2019Article
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3 authors.
Funding
Abstract
Copper-catalyzed alkene amino oxygenation reactions using O-acylhydroxylamines have been achieved for a rapid and modular access to diverse 1,2-amino oxygen-containing molecules. This transformation is applicable to the use of alcohols, carbonyls, oximes, and thio-carboxylic acids as nucleophiles on both terminal and internal alkenes. Mild reaction conditions tolerate a wide range of functional groups, including ether, ester, amide, carbamate, and halide. The reaction protocol allows for starting with free amines as the precursor of O-benzoylhydroxylamines to eliminate their isolation and purification, contributing to broader synthetic utilities. Mechanistic investigations reveal the amino oxygenation reactions may involve distinct pathways, depending on different oxygen nucleophiles.
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