Evidence map›Paper›PMID 30588625›Full record

ArticleThe Laryngoscope2019

Management of difficult airway among patients with oropharyngeal angioedema.

Vinciya Pandian, Gooi Zhen, Stanola Stanley, Marco Oldsman, Elliott Haut, Lynette Mark, Christina Miller, Alexander Hillel

Open access · greenAbstract readEvaluation Study
In one paragraph

Article in The Laryngoscope, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Medical Malpractice in the Management of Angioedema: A Multidisciplinary Westlaw Analysis.World journal of otorhinolaryngology - head and neck surgery · 2026
    Article
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Vinciya PandianJohns Hopkins School of Nursing, Baltimore, Maryland.ORCID 0000-0002-2260-1080
Gooi ZhenUniversity of Chicago Medicine, Chicago, Illinois, U.S.A.
Stanola StanleyJohns Hopkins School of Nursing, Baltimore, Maryland.
Marco OldsmanJohns Hopkins School of Nursing, Baltimore, Maryland.
Elliott HautThe Division of Acute Care Surgery, Department of Surgery; Department of Anesthesiology and Critical Care Medicine; Department of Emergency Medicine, Baltimore, Maryland.
Lynette MarkThe Department of Anesthesiology and Critical Care Medicine, Baltimore, Maryland.
Christina MillerThe Department of Anesthesiology and Critical Care Medicine, Baltimore, Maryland.
Alexander HillelThe Department of Otolaryngology Head and Neck Surgery, Johns Hopkins School of Medicine, Baltimore, Maryland.ORCID 0000-0001-8471-5449
Johns Hopkins University · USUniversity of Maryland, Baltimore · USUniversity of Illinois Chicago · US

Funding

Individualized Performance Feedback on Venous Thromboembolism Prevention PracticeR01HS024547 · AHRQ · JOHNS HOPKINS UNIVERSITY · PI HAUT, ELLIOTT R · 2016 to 2020
$1.2M
Immune Cell Modulation in Laryngotrachael FibrosisK23DC014082 · NIDCD · JOHNS HOPKINS UNIVERSITY · PI HILLEL, ALEXANDER · 2015 to 2019
$1.2M
Metabolic Reprogramming in Laryngotracheal StenosisR21DC017225 · NIDCD · JOHNS HOPKINS UNIVERSITY · PI HILLEL, ALEXANDER · 2018 to 2020
$491k
AHRQ HHS R01 HS024547NIDCD NIH HHS K23 DC014082NIDCD NIH HHS R21 DC017225Patient-Centered Outcomes Research Institute CE-12-11-4489
6 · The paper itself

Abstract

objectiveThe objective of our study was to assess the impact of a multidisciplinary difficult airway response team (DART), a quality improvement program, in the management of patients with difficult airway associated with oropharyngeal angioedema patients.

methodsIndividual retrospective cohort study. Retrospective review of patient charts from July 2003 to June 2008 (pre-DART) and retrospective review of prospectively collected data from July 2008 to June 2013 (post-DART). Patients with angioedema were identified using International Classification of Disease codes 995.1 and 277.6. Patients were included in the study if an otolaryngologist was consulted for airway management. Patients were excluded if they had a history of angioedema but no active issues. Patient characteristics, airway evaluation, and interventions (intubation/surgical airway) were compared between the pre-DART and post-DART cohort.

resultsThe DART team attended to 27 patients with advanced oropharyngeal angioedema. Response time averaged 3.36 minutes. Preintubation fiberoptic airway evaluations were performed in 81% of the post-DART cohort and 56% of the pre-DART cohort. The incidence of patients requiring intubation was higher in the post-DART cohort (18 out of 27 [67%]) than the pre-DART (14 out of 36 [39%]) cohort. One emergency cricothyroidotomy was performed in each of the post-DART and pre-DART cohorts.

conclusionAngioedema of the larynx is a predictor of intubation or cricothyroidotomy. Fiberoptic-guided intubation is primarily used for establishing airway in angioedema patients. A multidisciplinary standardized approach such as the DART program offers adequate time and resources for airway evaluation prior to intervention and allows fewer number of attempts to secure an airway. LEVEL OF EVIDENCE: 3 Laryngoscope, 129:1360-1367, 2019.

Indexed as

Quality ImprovementAdultAgedAirway ManagementAngioedemaFemaleFiber Optic TechnologyHumansIntubation, IntratrachealMaleMiddle AgedOropharynxPatient Care TeamProspective StudiesRetrospective StudiesTertiary Care Centersairway securement techniquesclinical outcomesdifficult airwaymultidisciplinaryOropharyngeal angioedema

Identifiers

PMID30588625
PMCPMC6525056
OpenAlexW2907815511

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.