ArticleAnnals of hepato-biliary-pancreatic surgery2018
Predictive value of post-operative drain amylase levels for post-operative pancreatic fistula.
Article in Annals of hepato-biliary-pancreatic surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 14 citations in OpenAlex.
- The Predictive Effect of "Real Amylase Value": A More Accurate Predictor for Postoperative Pancreatic Fistula.ANZ journal of surgery · 2025Article
- Drainage volume on postoperative day one to predict clinically relevant postoperative pancreatic fistula following distal pancreatectomy.BMC surgery · 2022Article
- Intrapancreatic accessory spleen with an epidermoid cyst: a malignant mimicry.BMJ case reports · 2022Article
- Pancreaticoduodenectomy after Roux-en-Y Gastric Bypass: a novel reconstruction technique.Translational gastroenterology and hepatology · 2022Article
- Lymphopenia following pancreaticoduodenectomy is associated with pancreatic fistula formation.Annals of hepato-biliary-pancreatic surgery · 2021Article
- Impact of continuous local lavage on pancreatic juice-related postoperative complications: Three case reports.World journal of clinical cases · 2019Article
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUNDS/
aimsTraditionally, surgically placed pancreatic drains are removed, at the discretion of the operating surgeon. Moving towards enhanced recovery after surgery (ERAS), we looked for predictors for early drain removal. The purpose of this paper was to establish which postoperative days' (POD) drain amylase is most predictive against post-operative pancreatic fistula (POPF).
methodsWe conducted a retrospective study of 196 patients who underwent pancreatic resection at our institute from January 2006 to October 2013. Drain amylase levels were routinely measured. The International Study Group of Pancreatic Fistula (ISGPF) definition of POPF, and clinical severity grading were used.
results5.1% (10 of 196) patients developed ISGPF Grades B and C POPF. Negative predictive value of developing significant POPF, if drain amylase values were low on PODs 1 and 3 was 98.7% (95% CI: 0.93-1.00). This translated to confidence in removing surgically placed pancreatic drains, at POD 1 and 3 when drain amylase values are low.
conclusionsPatients with low drain amylase values on POD 1 and 3, are unlikely to develop POPF and may have pancreatic drains removed earlier.
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