Evidence map›Paper›PMID 30588428›Full record

ArticleInternational journal of ophthalmology2018

Long term follow-up of a family with

Georgios Tsokolas, Hussein Almuhtaseb, Helen Griffiths, Fatima Shawkat, Reuben J Pengelly, Ennis Sarah, Andrew Lotery

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of ophthalmology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Genes · 2022
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Georgios TsokolasClinical and Experimental Sciences, University of Southampton, Southampton, Hampshire SO16 6YD, UK.
Hussein AlmuhtasebClinical and Experimental Sciences, University of Southampton, Southampton, Hampshire SO16 6YD, UK.
Helen GriffithsClinical and Experimental Sciences, University of Southampton, Southampton, Hampshire SO16 6YD, UK.
Fatima ShawkatEye Unit, University Hospital Southampton, Southampton, Hampshire SO16 6YD, UK.
Reuben J PengellyHuman Genetics & Genomic Medicine, Faculty of Medicine, University of Southampton, Southampton, Hamphsire, SO16 6YD, UK.
Ennis SarahHuman Genetics & Genomic Medicine, Faculty of Medicine, University of Southampton, Southampton, Hamphsire, SO16 6YD, UK.
Andrew LoteryClinical and Experimental Sciences, University of Southampton, Southampton, Hampshire SO16 6YD, UK.
University of Southampton · GBSouthampton Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo describe long term follow-up in a family with

methodsOptical coherence tomography scans and fundus autofluorescence images were obtained. Flash and pattern electroretinograms (ERGs) and occipital pattern reversal visual evoked potentials were recorded.

resultsTwo members of the same family (father and son) were identified to have the heterozygous R838C mutation in the

conclusionBoth family members exhibited gradual changes in their fundi, electrophysiological testing and multimodal imaging. Changes were milder than those observed in other mutations of the same gene.

Indexed as

autofluorescencecone dystrophycone-rod dystrophyelectroretinogramGUCY2Dspectral-domain optical coherence tomographyvisual evoked potential

Identifiers

PMID30588428
PMCPMC6288524
OpenAlexW2909470001

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.