ArticleInternational journal of ophthalmology2018
Factors influencing subjective symptoms in dry eye disease.
Article in International journal of ophthalmology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.
- Pooled it
- Trial
- Diurnal Variation, Topographical Distribution and Day-to-Day Repeatability of Ocular Surface Epithelial Immune Cells in Individuals with Dry Eye Disease.Journal of clinical medicine · 2026Article
- Precise longitudinal monitoring of corneal change through in vivo confocal microscopy in a rat dry eye disease model.Molecular vision · 2024Article
- Evaluation of Ocular Surface after Cataract Surgery-A Prospective Study.Journal of clinical medicine · 2022Article
- Voluntary wheel-running activities ameliorate depressive-like behaviors in mouse dry eye models.Frontiers in behavioral neuroscience · 2022Article
- Reliability of Chinese web-based ocular surface disease index questionnaire in dry eye patients: a randomized, crossover study.International journal of ophthalmology · 2021Article
- Changes of tear film lipid layer thickness by 3% diquafosol ophthalmic solutions in patients with dry eye syndrome.International journal of ophthalmology · 2019Article
- Artificial Intelligence in Clinical Diagnosis and Treatment of Dry Eye: Workflows, Effectiveness, and Evaluation.Journal of current ophthalmologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo retrospectively investigate the association between dry eye symptoms and clinical or
methodsThis retrospective, cross-sectional, controlled study comprised 25 consecutive patients with non-Sjögren dry eye disease and age- and sex-matched 25 healthy subjects. Each patient underwent a complete examination of the ocular surface in the following order: tear osmolarity measurements, InflammaDry test, tear break-up time, corneal fluorescein staining, Schirmer I test, subjective symptoms questionnaire using the dry eye-related quality-of-life score (DEQS), and
resultsIn univariate analysis, DEQS was associated with tear break-up time (
conclusionOur study shows a significant association between depression and dry eye symptoms. It suggests that dry eye symptoms associate with higher depressive symptoms and its medications, although our patients were not followed longitudinally.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.