Evidence map›Paper›PMID 30588291›Full record

ArticleHealth information science and systems2019

Neural networks for mining the associations between diseases and symptoms in clinical notes.

Setu Shah, Xiao Luo, Saravanan Kanakasabai, Ricardo Tuason, Gregory Klopper

Abstract read
In one paragraph

Article in Health information science and systems, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Setu Shah1Purdue School of Engineering and Technology, IUPUI, 799 W. Michigan Street, Indianapolis, IN 46202 USA.
Xiao Luo1Purdue School of Engineering and Technology, IUPUI, 799 W. Michigan Street, Indianapolis, IN 46202 USA.ORCID 0000-0002-3649-9785
Saravanan Kanakasabai2Indiana University Health South Campus, 1515 N. Senate Ave, Indianapolis, IN 46202 USA.
Ricardo Tuason2Indiana University Health South Campus, 1515 N. Senate Ave, Indianapolis, IN 46202 USA.
Gregory Klopper2Indiana University Health South Campus, 1515 N. Senate Ave, Indianapolis, IN 46202 USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There are challenges for analyzing the narrative clinical notes in Electronic Health Records (EHRs) because of their unstructured nature. Mining the associations between the clinical concepts within the clinical notes can support physicians in making decisions, and provide researchers evidence about disease development and treatment. In this paper, in order to model and analyze disease and symptom relationships in the clinical notes, we present a concept association mining framework that is based on word embedding learned through neural networks. The approach is tested using 154,738 clinical notes from 500 patients, which are extracted from the Indiana University Health's Electronic Health Records system. All patients are diagnosed with more than one type of disease. The results show that this concept association mining framework can identify related diseases and symptoms. We also propose a method to visualize a patients' diseases and related symptoms in chronological order. This visualization can provide physicians an overview of the medical history of a patient and support decision making. The presented approach can also be expanded to analyze the associations of other clinical concepts, such as social history, family history, medications, etc.

Indexed as

Clinical notesConcept association miningElectronic health recordsNatural language processingNeural networks

Identifiers

PMID30588291
PMCPMC6261925

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.