Evidence map›Paper›PMID 30588142›Full record

ArticleJournal of blood medicine2018

Al-hijamah (wet cupping therapy of prophetic medicine) significantly and safely reduces iron overload and oxidative stress in thalassemic children: a novel pilot study.

Mohamed El-Shanshory, Nahed M Hablas, Yasmin Shebl, Ahmed R Fakhreldin, Mohamed Attia, Hamdi H Almaramhy, Hussam Baghdadi, Mongi Ayat, Amal Albeihany, Amr El-Dardear and 4 more

Open access · goldAbstract read
In one paragraph

Article in Journal of blood medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 2 countries.

Mohamed El-ShanshoryProphetic Medicine Course and Research, Taibah College of Medicine, Medina, Saudi Arabia, salahfazara@yahoo.com.
Nahed M HablasDepartment of Pediatrics, Tanta University Faculty of Medicine, Tanta Gharbia, Egypt.
Yasmin SheblDepartment of Pediatrics, Tanta University Faculty of Medicine, Tanta Gharbia, Egypt.
Ahmed R FakhreldinDepartment of Pediatrics, Aswan Faculty of Medicine, Aswan University, Aswan, Egypt.
Mohamed AttiaDepartment of Clinical Pathology, Tanta Faculty of Medicine, Tanta University, Tanta, Egypt.
Hamdi H AlmaramhyDepartment of Surgery, Taibah Faculty of Medicine, Taibah University, Medina, Saudi Arabia.
Hussam BaghdadiDepartment of Clinical Biochemistry and Molecular Medicine, Taibah Faculty of Medicine, Taibah University, Medina, Saudi Arabia, salahfazara@yahoo.com.
Mongi AyatProphetic Medicine Course and Research, Taibah College of Medicine, Medina, Saudi Arabia, salahfazara@yahoo.com.
Amal AlbeihanyDepartment of Hematology, King Fahd Hospital, Ministry of Health, Medina, Saudi Arabia.
Amr El-DardearProphetic Medicine Course and Research, Taibah College of Medicine, Medina, Saudi Arabia, salahfazara@yahoo.com.
Hoda Ali IbrahimDepartment of Biochemistry, Tanta Faculty of Medicine, Tanta University, Tanta, Egypt.
Hany Salah MahmoudScientific Center for Experimental and Research Studies, Cairo, Egypt.
Manal Mohamed Helmy NaboDivision of Pediatric Intensive Care Unit, King Fahad Hospital, Ministry of Health, Medina, Saudi Arabia.
Salah Mohamed El SayedProphetic Medicine Course and Research, Taibah College of Medicine, Medina, Saudi Arabia, salahfazara@yahoo.com.
Tanta University · EGTaibah University · SAMinistry of Health · SAAswan University · EGCairo University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThalassemia is a major health problem due to iron overload, iron deposition and oxidative stress-induced tissue damage. Here, we introduce Al-hijamah (a minor surgical excretory procedure) as a novel percutaneous iron excretion therapy. Al-hijamah is a wet cupping therapy of prophetic medicine, and prophet Muhammad, peace be upon him, strongly recommended Al-hijamah, saying: "The best of your treatment is Al-hijamah". AIM OF THE STUDY: Our study aimed at investigating the safety, iron chelation, pharmacological potentiation and oxidant clearance effects exerted by Al-hijamah to thalassemic children. PATIENTS AND

methodsEthical committee's approval and patients' written agreement consents were obtained. We treated 20 thalassemic children (15 males and five females aged 9.07±4.26 years) with iron chelation therapy (ICT) plus Al-hijamah (using sterile disposable sets and in a complete aseptic environment) vs a control group treated with ICT only. This clinical trial was registered in the ClinicalTrial.gov registry under the name "Study of the Therapeutic Benefits of Al-hijamah in Children with Beta Thalassemia Major" (identifier no NCT 02761395) on 30 January 2016.

resultsAl-hijamah was quite simple, safe, effective, tolerable (with no side effects) and time-saving procedure (30-60 minutes). A single session of Al-hijamah significantly reduced iron overload (

conclusionAl-hijamah is a novel, safe, effective percutaneous iron excretion therapy through percutaneous iron excretion with minimal blood loss in agreement with the evidence-based Taibah mechanism. Al-hijamah is an effective outpatient hematological procedure that is safer than many pediatric procedures such as catheterization, hemofiltration and dialysis. Increasing the number of cups during Al-hijamah session or the number of sessions reduces iron overload more strongly. Medical practice of Al-hijamah is strongly recommended in hospitals.

Indexed as

Al-hijamahAl-hijamah indicesclearanceiron chelation therapyoxidative stressthalassemia

Identifiers

PMID30588142
PMCPMC6300367
OpenAlexW2904870985

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.