ArticleInternational journal of chronic obstructive pulmonary disease
Strain measurement on four-dimensional dynamic-ventilation CT: quantitative analysis of abnormal respiratory deformation of the lung in COPD.
Article in International journal of chronic obstructive pulmonary disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Chest CT in the evaluation of chronic obstructive pulmonary disease: recommendations of Asian Society of Thoracic Radiology.The British journal of radiology · 2026Guideline
- Impaired lung deformation during expiration in chronic obstructive pulmonary disease using four-dimensional dynamic-ventilation CT.Quantitative imaging in medicine and surgery · 2026Article
- Investigation into the utility of ultra-high-resolution mode on dynamic-ventilation computed tomography using sponge phantoms.Scientific reports · 2025Article
- Towards constructing a generalized structural 3D breathing human lung model based on experimental volumes, pressures, and strains.PLoS computational biology · 2025Article
- 4D-CT strain analysis for biomechanical characterization of COPD in patients undergoing radiotherapy planning: an exploratory study.Frontiers in medicine · 2025Article
- Regional ventilation dynamics of electrical impedance tomography validated with four-dimensional computed tomography: single-center, prospective, observational study.Critical care (London, England) · 2024Observational
- Right main pulmonary artery distensibility on dynamic ventilation CT and its association with respiratory function.European radiology experimental · 2024Article
- Area-Detector Computed Tomography for Pulmonary Functional Imaging.Diagnostics (Basel, Switzerland) · 2023Review
- Strain Analysis in Patients at High-Risk for COPD Using Four-Dimensional Dynamic-Ventilation CT.International journal of chronic obstructive pulmonary disease · 2022Article
- Difference in Local Lung Movement During Tidal Breathing Between COPD Patients and Asthma Patients Assessed by Four-dimensional Dynamic-ventilation CT Scan.International journal of chronic obstructive pulmonary disease · 2020Article
- Influence of Emphysema and Air Trapping Heterogeneity on Pulmonary Function in Patients with COPD.International journal of chronic obstructive pulmonary disease · 2019Article
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8 authors.
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Abstract
purposeStrain measurement is frequently used to assess myocardial motion in cardiac imaging. This study aimed to apply strain measurement to pulmonary motion observed by four-dimensional dynamic-ventilation computed tomography (CT) and to clarify motion abnormality in COPD. MATERIALS AND
methodsThirty-two smokers, including ten with COPD, underwent dynamic-ventilation CT during spontaneous breathing. CT data were continuously reconstructed every 0.5 seconds. In the series of images obtained by dynamic-ventilation CT, five expiratory frames were identified starting from the peak inspiratory frame (first expiratory frame) and ending with the fifth expiratory frame. Strain measurement of the scanned lung was performed using research software that was originally developed for cardiac strain measurement and modified for assessing deformation of the lung. The measured strain values were divided by the change in mean lung density to adjust for the degree of expiration. Spearman's rank correlation analysis was used to evaluate associations between the adjusted strain measurements and various spirometric values.
resultsThe adjusted strain measurement was negatively correlated with FEV
conclusionAbnormal deformation of lung motion exists in COPD patients and can be quantitatively assessed by strain measurement using dynamic-ventilation CT. This technique can be expanded to dynamic-ventilation CT in patients with various lung and airway diseases that cause abnormal pulmonary motion.
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