Trial reportHypertension research : official journal of the Japanese Society of Hypertension2019
Combined use of a healthy lifestyle smartphone application and usual primary care counseling to improve arterial stiffness, blood pressure and wave reflections: a Randomized Controlled Trial (EVIDENT II Study).
Trial report in Hypertension research : official journal of the Japanese Society of Hypertension, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 18 citations in OpenAlex.
- Pooled it
- Effectiveness of digital health interventions for telemedicine/telehealth for managing blood pressure in adults: a systematic review and meta-analysis.Hypertension research : official journal of the Japanese Society of Hypertension · 2025Pooled it
- Trial
- Effectiveness of the Internet of Things for Improving Health of Non-Pregnant Women Living in High-Income Countries: A Systematic Review.Healthcare (Basel, Switzerland) · 2025Review
- Advancing clinical research in the Spanish primary care service: Challenges, opportunities, and lessons from other European models.The European journal of general practice · 2025Article
- Effectiveness of the Internet of Things for Improving Working-Aged Women's Health in High-Income Countries: Protocol for a Systematic Review and Network Meta-analysis.JMIR research protocols · 2023Article
- The Effectiveness of a Mobile Health Care App and Human Coaching Program in Primary Care Clinics: Pilot Multicenter Real-World Study.JMIR mHealth and uHealth · 2022Article
- Nutrition and physical activity interventions for the general population with and without cardiometabolic risk: a scoping review.Public health nutrition · 2021Article
- Mobile health strategies for blood pressure self-management in urban populations with digital barriers: systematic review and meta-analyses.NPJ digital medicine · 2021Review
- Randomized, "head-to-head" studies comparing different SGLT2 inhibitors are definitely needed.Journal of clinical hypertension (Greenwich, Conn.) · 2020Article
- Physician and patient perspectives on hypertension management and factors associated with lifestyle modifications in Japan: results from an online survey.Hypertension research : official journal of the Japanese Society of Hypertension · 2020Article
- Perspectives of patients and physicians regarding hypertensive management from an online survey for excellence: a subanalysis of the PARADOX study by physician categories.Hypertension research : official journal of the Japanese Society of Hypertension · 2020Article
- Association between ideal cardiovascular health score trajectories and arterial stiffness: the Kailuan Study.Hypertension research : official journal of the Japanese Society of Hypertension · 2020Article
Corrections and comments
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Authors and funding
10 authors at 6 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Our aim was to investigate the effects of an intervention that comprised a brief counseling session on lifestyle habits together with the use of the EVIDENT (Lifestyles and arterial aging) application on the modification of markers that indicated different hemodynamic functions, such as arterial stiffness, blood pressure or wave reflections. The EVIDENT II study (Lifestyles and arterial aging) is a randomized clinical trial with two parallel groups. Each participant had an initial visit and two follow-up visits at 3 and 12 months where the peripheral augmentation index-PAIx75 was measured by tonometry, while an oscillometric method was used for the cardio-ankle vascular index-CAVI and brachial-ankle pulse wave velocity-baPWV. Both groups (intervention-IG and control-CG) were briefly counseled on diet and exercise. The IG also received instructions on the use of the EVIDENT II application during the 3 months. The sample (N = 597; 52 ± 11 years; 64% women) was randomized into IG = 291 and CG = 306. Comparing groups, there was a decrease in the PAIx75 favorable to the IG at 3 months (-4.9%, 95% CI: -7.7 to -2.1) and 12 months (-3.9%, 95% CI: -6.8 to -1.0). There was also a nonsignificant reduction of the CAVI at 3 months in the IG. A group effect was observed in the measurement of the PAIx75 over the 12-month follow-up (p = 0.003). This interaction was only observed in women (p = 0.017). In conclusion, the use of the EVIDENT II application achieved a modification of the PAIx75, a marker of wave reflection and vascular tone, in women through lifestyle improvements (physical activity and adherence to the Mediterranean diet). No significant results were found regarding blood pressure or arterial stiffness markers.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.