Observational studyPediatric research2019
Cerebral oxygenation in preterm infants receiving transfusion.
Observational study in Pediatric research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 4 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
11 citing papers in PubMed, 4 syntheses or guidelines pooled it, 15 citations in OpenAlex.
- The Effect of Liberal versus Restrictive Haemoglobin Thresholds on Cerebral Tissue Oxygenation in Preterm Infants: A Systematic Review and Meta-Analysis.Neonatology · 2026Pooled it
- The near-infrared spectroscopy to evaluate neonatal improvement after transfusion: a systematic review and meta-analysis.BMC pediatrics · 2025Pooled it
- A recommendation for the use of electrical biosensing technology in neonatology.Pediatric research · 2025Guideline
- Anemia and Red Blood Cell Transfusions, Cerebral Oxygenation, Brain Injury and Development, and Neurodevelopmental Outcome in Preterm Infants: A Systematic Review.Frontiers in pediatrics · 2021Pooled it
- Tissue Oxygenation Changes After Transfusion and Outcomes in Preterm Infants: A Secondary Near-Infrared Spectroscopy Study of the Transfusion of Prematures Randomized Clinical Trial (TOP NIRS).JAMA network open · 2023Trial
- Impact of level of neonatal care on phlebotomy and blood transfusion in extremely low birthweight infants: a prospective, multicenter, observational study.Frontiers in pediatrics · 2023Article
- Early brain and abdominal oxygenation in extremely low birth weight infants.Pediatric research · 2022Article
- Regional tissue oxygenation and conventional indicators of red blood cell transfusion in anaemic preterm infants.EClinicalMedicine · 2022Article
- Transfusion prevention using erythropoietin, parenteral sucrose iron, and fewer phlebotomies in infants born at ≤30 weeks gestation at a high altitude center: a 10-year experience.Journal of perinatology : official journal of the California Perinatal Association · 2021Article
- Analysis of correlative risk factors for blood transfusion therapy for extremely low birth weight infants and extreme preterm infants.American journal of translational research · 2021Article
- Non-invasive Cardiac Output Monitoring in Neonates.Frontiers in pediatrics · 2020Review
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe influence of severity of anemia and cardiac output (CO) on cerebral oxygenation (CrSO
methodsPreterm infants of <32 weeks gestational age (GA) receiving PRBC transfusion were enrolled. Infants received 15 ml/kg PRBC over 3 h. CrSO
resultsThirty infants of 26.6 ± 2.0 weeks GA were studied at 19 ± 12 days. Pre-transfusion Hb was 9.8 ± 0.6 g/dl. Pre-transfusion CrSO
conclusionIn these infants, the pre-transfusion ODI was a better indicator of brain oxygenation and its improvement post transfusion than Hb alone. The role of CO and tissue oxygenation monitoring in assessing the need for transfusion should be evaluated.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.