Evidence map›Paper›PMID 30587834›Full record

ArticleInternational journal of molecular sciences2018

Synthetic Tyrosine tRNA Molecules with Noncanonical Secondary Structures.

Kensaku Sakamoto, Akiko Hayashi

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Genetic Code Expansion: Another Solution to Codon Assignments.International journal of molecular sciences · 2022
    Article
  4. Directed Evolution of theInternational journal of molecular sciences · 2021
    Article
  5. Article
  6. Rational Design of Aptamer-Tagged tRNAs.International journal of molecular sciences · 2020
    Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Kensaku SakamotoLaboratory for Nonnatural Amino Acid Technology, RIKEN Center for Biosystems Dynamics Research (BDR), 1-7-22 Suehiro-cho, Tsurumi, Yokohama 230-0045, Japan. kensaku.sakamoto@riken.jp.ORCID 0000-0003-2866-5031
Akiko HayashiLaboratory for Nonnatural Amino Acid Technology, RIKEN Center for Biosystems Dynamics Research (BDR), 1-7-22 Suehiro-cho, Tsurumi, Yokohama 230-0045, Japan. akiko.matsumoto@riken.jp.
RIKEN Center for Biosystems Dynamics Research · JP

Funding

Japan Society for the Promotion of Science KAKENHI 18H02416
6 · The paper itself

Abstract

The L-shape form of tRNA is maintained by tertiary interactions occurring in the core. Base changes in this domain can cause structural defects and impair tRNA activity. Here, we report on a method to safely engineer structural variations in this domain utilizing the noncanonical scaffold of tRNA

Indexed as

Base SequenceCodon, TerminatorEscherichia coliMethanosarcinaMonoiodotyrosineNucleic Acid ConformationRNA, Transfer3-iodotyrosineCodon, TerminatorMonoiodotyrosineRNA, Transferamber suppressiongenetic code expansionpyrrolysine tRNAtertiary base pairstRNA secondary structure

Identifiers

PMID30587834
PMCPMC6337575
OpenAlexW2905865631

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.